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ABSTRACT Advanced paternal age is linked to complications in pregnancy and genetic diseases in offspring. Aging results in excess… Expand Hyperbaric oxygen (HBO), e.g. pure oxygen breathing at supra-atmospheric pressures, represents a well-suited model for… Expand SummaryThe chemoattractants, N-formyl-L-methio-nyl-L-leucyl-L-phenylalanine (fMet-Leu-Phe), complement C5a and platelet… Expand In this study the effect of increased nitric oxide (NO) production on the expression of rat liver heme oxygenase-1, an inducible… Expand The bioavailability and pharmacokinetics of molsidomine (SIN-10) from a capsule containing wax-coated beads, were compared with… Expand Based on the lumped parameter Windkessel theory, compliance of the aorta of anesthetized dogs was calculated in vivo. The formula… Expand The studies on structure and action of 3-substituted sydnonimines and their ring-opened derivatives (1, 2) indicated that… Expand Sydnonimine derivatives, a series of mesoionic compounds, have a peculiar feature in their molecular structure and biological… Expand 5-Ethoxycarbonyl-3-morpholinosydnonimine (SIN-10), synthesized by Masuda et al. (1) is one of sydnonimine derivatives with… Expand Effects of the sydnonimine derivatives on cardiovascular system have been studied (1-5), and the results in our laboratory are… Expand