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Molsidomine

Known as: Sydnone imine, N-(ethoxycarbonyl)-3-(4-morpholinyl)-, Morsydomine, Molsidomin 
A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has… 
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (12)

CorpeaCorvatonFali-CorMTW-Molsidomin
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (2)

Nitric Oxide DonorsVasodilator Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Comparing Generic Drug Markets in Europe and the United States: Prices, Volumes, and Spending
Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United… 
Highly Cited
2011
Highly Cited
2011
Nitric Oxide Sustains Long-Term Skeletal Muscle Regeneration by Regulating Fate of Satellite Cells Via Signaling Pathways Requiring Vangl2 and Cyclic GMP
Satellite cells are myogenic precursors that proliferate, activate, and differentiate on muscle injury to sustain the… 
Highly Cited
2005
Highly Cited
2005
l-arginine improves dystrophic phenotype in mdx mice
Highly Cited
2004
Highly Cited
2004
Discovering Modes of Action for Therapeutic Compounds Using a Genome-Wide Screen of Yeast Heterozygotes
Highly Cited
1996
Highly Cited
1996
Clinical Pharmacokinetics of Molsidomine
SummaryMolsidomine is a prodrug for the formation of nitric oxide (NO). Its pharmacokinetics are characterised by rapid… 
Highly Cited
1996
Highly Cited
1996
Nitric Oxide Donors SIN-1 and SNAP Promote Nonrapid-Eye-Movement Sleep in Rats
Highly Cited
1995
Highly Cited
1995
Pharmacological evidence that nitric oxide can act as an endogenous antipyretic factor in endotoxin-induced fever in rabbits.
Highly Cited
1990
Highly Cited
1990
Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP.
We investigated the roles of cyclic GMP and cyclic AMP in the inhibition of rabbit platelet aggregation and degranulation by two… 
Highly Cited
1988
Highly Cited
1988
Direct comparison of the effects of nitroprusside, SIN 1, and various nitrates on platelet aggregation and soluble guanylate cyclase activity.
Highly Cited
1980
Highly Cited
1980
Molsidomine in the treatment of patients with angina pectoris.
Molsidomine, a new long-acting vasodilator, was administered intravenously (0.03 mg per kilogram of body weight) to two groups of… 
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