SHANK1 gene

Known as: SH3 and multiple ankyrin repeat domains 1, synamon, SPANK-1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2017
02420112017

Papers overview

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2017
2017
Recent studies have strongly suggested a role for the synaptic scaffolding protein SHANK1 in normal synaptic structure and… (More)
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2016
2016
Autism-related Shank1, Shank2, and Shank3 are major postsynaptic scaffold proteins of excitatory glutamatergic synapses. A few… (More)
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2016
2016
Significant losses of synapses have been demonstrated in studies of Alzheimer's disease (AD), but structural and functional… (More)
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2016
2016
Members of the Shank family of multidomain proteins (Shank1, Shank2, and Shank3) are core components of the postsynaptic density… (More)
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Review
2015
Review
2015
Autism spectrum disorders (ASD) are highly heterogeneous pediatric developmental disorders with estimated heritability more than… (More)
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2014
2014
SHANK genes code for scaffold proteins located at the post-synaptic density of glutamatergic synapses. In neurons, SHANK2 and… (More)
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2013
2013
Synaptopathies constitute a group of neurological diseases including autism spectrum disorders (ASD) and intellectual disability… (More)
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Highly Cited
2012
Highly Cited
2012
Recent studies have highlighted the involvement of rare (<1% frequency) copy-number variations and point mutations in the genetic… (More)
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Highly Cited
2011
Highly Cited
2011
Autism is a neurodevelopmental disorder with a strong genetic component. Core symptoms are abnormal reciprocal social… (More)
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2011
2011
Mutations in postsynaptic scaffolding genes contribute to autism, thus suggesting a role in pathological processes in… (More)
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