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SH3RF1 gene

Known as: SH3RF1, POSH, plenty of SH3 domains 
National Institutes of Health

Papers overview

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2018
2018
Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth
Oncogenic lesions are surprisingly common in morphologically and functionally normal human skin. However, the cellular and… 
Highly Cited
2015
Highly Cited
2015
Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia
Rab8, POSH, and TAK1 regulate synaptic growth responses, which suggests that recycling endosomes are key compartments for… 
Highly Cited
2013
Highly Cited
2013
Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study
Background:Black ethnic groups have a higher breast cancer mortality than Whites. American studies have identified variations in… 
Review
2012
Review
2012
Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study
Aims (1) To compare the use of scanned virtual slide images (virtual microscopy) with glass slides (conventional microscopy) in… 
2009
2009
Role of Rac1 GTPase in JNK signaling and delayed neuronal cell death following global cerebral ischemia
Highly Cited
2006
Highly Cited
2006
Direct Interaction of the Molecular Scaffolds POSH and JIP Is Required for Apoptotic Activation of JNKs*
A sequential pathway (the JNK pathway) that includes activation of Rac1/Cdc42, mixed lineage kinases, MAP kinase kinases 4 and 7… 
Highly Cited
2005
Highly Cited
2005
The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production.
HIV type 1 (HIV-1) was shown to assemble either at the plasma membrane or in the membrane of late endosomes. Now, we report an… 
Highly Cited
2005
Highly Cited
2005
Regulation of Apoptotic c-Jun N-Terminal Kinase Signaling by a Stabilization-Based Feed-Forward Loop
ABSTRACT A sequential kinase cascade culminating in activation of c-Jun N-terminal kinases (JNKs) plays a fundamental role in… 
Highly Cited
2003
Highly Cited
2003
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis
We report that the multidomain protein POSH (plenty of SH3s) acts as a scaffold for the JNK pathway of neuronal death. This… 
Highly Cited
1998
Highly Cited
1998
A new Rac target POSH is an SH3‐containing scaffold protein involved in the JNK and NF‐κB signalling pathways
The Rho, Rac and Cdc42 GTPases coordinately regulate the organization of the actin cytoskeleton and the JNK MAP kinase pathway… 
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