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SH2B1 wt Allele

Known as: DKFZP547G1110, SH2B Adaptor Protein 1 wt Allele, SH2-B Homolog Gene 
Human SH2B1 wild-type allele is located in the vicinity of 16p11.2 and is approximately 27 kb in length. This allele, which encodes SH2B adaptor… 
National Institutes of Health

Related topics

Related topics

5 relations
16p11.2SH2B protein, humanSignal Transductionprotein protein interaction

Broader (1)

SH2B1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS.
Highly Cited
2005
Highly Cited
2005
Kinase Activation through Dimerization by Human SH2-B
ABSTRACT The isoforms of SH2-B, APS, and Lnk form a family of signaling proteins that have been described as activators… 
2004
2004
Adapter Protein SH2-Bβ Undergoes Nucleocytoplasmic Shuttling: Implications for Nerve Growth Factor Induction of Neuronal Differentiation
ABSTRACT The adapter protein SH2-B has been shown to bind to activated nerve growth factor (NGF) receptor TrkA and has been… 
Highly Cited
2003
Highly Cited
2003
Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and…
Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B are adapter proteins and… 
Highly Cited
2001
Highly Cited
2001
Four PSM/SH2-B Alternative Splice Variants and Their Differential Roles in Mitogenesis*
An SH2 domain originally termed SH2-B had been identified as a direct cellular binding target of a number of mostly mitogenic… 
Highly Cited
2000
Highly Cited
2000
SH2-B Is Required for Growth Hormone-induced Actin Reorganization*
The Src homology-2 (SH2) domain-containing protein SH2-Bβ is a substrate of the growth hormone (GH) receptor-associated tyrosine… 
2000
2000
PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis
PSM/SH2-B has been described as a cellular partner of the FcεRI receptor, insulin receptor (IR), insulin-like growth factor-I… 
Highly Cited
1999
Highly Cited
1999
SH2-B, a Membrane-associated Adapter, Is Phosphorylated on Multiple Serines/Threonines in Response to Nerve Growth Factor by Kinases within the MEK/ERK Cascade*
SH2-B has been shown to be required for nerve growth factor (NGF)-mediated neuronal differentiation and survival, associate with… 
Highly Cited
1999
Highly Cited
1999
APS, an adapter protein with a PH and SH2 domain, is a substrate for the insulin receptor kinase.
APS (adapter protein with a PH and SH2 domain) is the newest member of a family of tyrosine kinase adapter proteins including SH2… 
Highly Cited
1997
Highly Cited
1997
PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor.
Insulin stimulation results in a considerable spectrum of cellular responses, only part of which have been firmly correlated with… 
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