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SH2B1 wt Allele

Known as: DKFZP547G1110, SH2B Adaptor Protein 1 wt Allele, SH2-B Homolog Gene 
Human SH2B1 wild-type allele is located in the vicinity of 16p11.2 and is approximately 27 kb in length. This allele, which encodes SH2B adaptor… Expand
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Src homology 2 (SH2) B adaptor protein 1 (SH2B1; originally named SH2-B) is a member of a family of adaptor proteins that… Expand
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Highly Cited
2005
Highly Cited
2005
Leptin regulates energy balance and body weight by activating its receptor LEPRb and multiple downstream signaling pathways… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Insulin regulates glucose homeostasis by binding and activating the insulin receptor, and defects in insulin responses… Expand
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Highly Cited
2004
Highly Cited
2004
Leptin regulates energy homeostasis primarily by binding and activating its long form receptor (LRb). Deficiency of either leptin… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Many growth factors and hormones modulate the reproductive status in mammals. Among these, insulin and insulin-like… Expand
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Highly Cited
2000
Highly Cited
2000
The Src homology-2 (SH2) domain-containing protein SH2-Bβ is a substrate of the growth hormone (GH) receptor-associated tyrosine… Expand
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Highly Cited
1999
Highly Cited
1999
Nerve growth factor (NGF) is essential for the development and survival of sympathetic and sensory neurons. NGF binds to TrkA… Expand
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Highly Cited
1998
Highly Cited
1998
Neurotrophins influence growth and survival of specific populations of neurons through activation of Trks, members of the… Expand
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Highly Cited
1997
Highly Cited
1997
Stimulation of B lymphocytes through their antigen receptor (BCR) results in rapid increases in tyrosine phosphorylation of a… Expand
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Highly Cited
1997
Highly Cited
1997
Insulin stimulation results in a considerable spectrum of cellular responses, only part of which have been firmly correlated with… Expand
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