SH2B1 gene

Known as: SH2-B homolog, SH2B ADAPTOR PROTEIN 1, SH2B1 
This gene plays a role in signal transduction. It is involved in both male and female reproduction.
National Institutes of Health

Papers overview

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2012
2012
Src homology 2 B adapter protein 1 (SH2B1) modulates signaling by a variety of ligands that bind to receptor tyrosine kinases or… (More)
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2010
2010
OBJECTIVE Recent genome-wide association studies have identified multiple novel loci associated with obesity in Europeans. We… (More)
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2010
2010
Weight gain is one of the major adverse effects of antipsychotics. Although mechanisms remain unclear, genetic susceptibility has… (More)
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Highly Cited
2009
Highly Cited
2009
Obesity results from the interaction of genetic and environmental factors. To search for sequence variants that affect variation… (More)
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Highly Cited
2009
Highly Cited
2009
Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To… (More)
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Review
2009
Review
2009
The brain controls energy homeostasis and body weight by integrating various metabolic signals. Leptin, an adipose-derived… (More)
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2009
2009
OBJECTIVE SH2B1 is a SH2 domain-containing adaptor protein expressed in both the central nervous system and peripheral tissues… (More)
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Highly Cited
2009
Highly Cited
2009
Recent genome-wide association studies (GWAS) have identified multiple risk loci for common obesity (FTO, MC4R, TMEM18, GNPDA2… (More)
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2008
2008
Previous work showed that the adapter protein SH2B adapter protein 1beta (SH2B1) (SH2-B) binds to the activated form of the nerve… (More)
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Review
2007
Review
2007
Src homology 2 (SH2) B adaptor protein 1 (SH2B1; originally named SH2-B) is a member of a family of adaptor proteins that… (More)
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