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SGI 1776

Known as: SGI-1776, SGI1776 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
PIM (proviral integration site for moloney murine leukemia virus) kinase plays a key role as an oncogene in various cancers… 
Highly Cited
2012
Highly Cited
2012
Proviral integration site for Moloney murine leukemia virus (Pim) kinases are serine/threonine/tyrosine kinases and oncoproteins… 
2012
2012
The PIM kinase inhibitor, SGI‐1776, was tested against the PPTP in vitro (1.0 nM–10 µM) and in vivo panels (148 mg/kg daily × 5… 
Highly Cited
2012
Highly Cited
2012
miRs play a critical role in tumor pathogenesis as either oncogenes or tumor-suppressor genes. However, the role of miRs and… 
2012
2012
To the editor: The Pim (for provirus integration site for Moloney murine leukemia virus) family of serine/threonine kinases are… 
Highly Cited
2011
Highly Cited
2011
Pim kinases are Ser/Thr kinases with multiple substrates that affect survival pathways. These proteins are overexpressed in acute… 
Review
2011
Review
2011
Pulmonary arterial hypertension (PAH) is a disease of the pulmonary vasculature characterized by constricted and remodeled… 
Highly Cited
2009
Highly Cited
2009
Pim kinases are involved in B-cell development and are overexpressed in B-cell chronic lymphocytic leukemia (CLL). We… 
Highly Cited
2009
Highly Cited
2009
The serine/threonine family of Pim kinases function as oncogenes and have been implicated in prostate cancer progression…