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SGI 1776

Known as: SGI-1776, SGI1776 
National Institutes of Health

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2 relations

Broader (2)

ImidazolesPyridazines

Papers overview

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2017
2017
Biochemical changes of salivary gland adenoid cystic carcinoma cells induced by SGI‐1776
2016
2016
Targeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition
The PIM family of proteins encodes serine/threonine kinases with important roles in protein synthesis and cancer cell metabolism… 
2015
2015
Pre-clinical evidence of PIM kinase inhibitor activity in BCR-ABL1 unmutated and mutated Philadelphia chromosome-positive (Ph+) leukemias
We investigated the efficacy of targeting the PIM kinase pathway in Philadelphia chromosome-positive (Ph+) leukemias. We provide… 
2012
2012
Studying c-Myc serine 62 phosphorylation in leukemia cells: concern over antibody cross-reactivity.
To the editor: A recent article in Blood demonstrated that the Pim kinase inhibitor SGI-1776 has efficacy in acute myeloid… 
2011
2011
PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells
The PIM family of oncogenic serine/threonine kinases regulates tumour cell proliferation. To identify proliferative signaling… 
2010
2010
Unitary Quantum Lattice Gas Algorithms for Quantum to Classical Turbulence
Using a set of interleaved unitary collision-stream operators, a three-dimensional (3D) quantum lattice gas algorithm is devised… 
2009
2009
Synergistic Activity of Co-Treatment with PIM1 Kinase Inhibitor SGI-1776 and Histone Deacetylase Inhibitor Panobinostat or Heat Shock Protein 90 Inhibitor AUY922 against Human CML and…
Abstract 2651 Poster Board II-627 The oncoprotein PIM1 is a cytoplasmic serine/threonine kinase, which is overexpressed and… 
2008
2008
Progress in Applying HPC to Support Operational Use of CT-Analyst
The objective of this effort is to perform the research and development (R&D) and systems engineering necessary to integrate… 
2008
2008
332 POSTER In vivo activity of SGI-1776, an orally active Pim kinase inhibitor
1981
1981
Soil Science Section, Water Research Centre, Elder Way, Stevenage, Hertfordshire SGI ITH, UK.
Results of field and pot trials aPe reported which have examined the transfer into crops of copper added to soil in sludge. A pot… 
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