SGI 1776

Known as: SGI-1776, SGI1776 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
02420002017

Papers overview

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2017
2017
Provirus integration site for Moloney murine leukemia virus 1 (Pim-1) has proved to be an oncogene and it is known that to… (More)
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2014
2014
OBJECTIVE To investigate the antitumor effect of SGI-1776 on human ovarian cancer HO-8910 cells and its molecular mechanism… (More)
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2013
2013
BACKGROUND Pim kinases are constitutively active serine/threonine/tyrosine kinases that are overexpressed in hematological… (More)
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2013
2013
BACKGROUND SGI-1776 is a small-molecule Pim kinase inhibitor that primarily targets c-MYC-driven transcription and cap-dependent… (More)
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2013
2013
Overexpression of the ATP-binding cassette (ABC) drug efflux proteins P-glycoprotein (ABCB1) and breast cancer resistance protein… (More)
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2012
2012
Proviral integration site for Moloney murine leukemia virus (Pim) kinases are serine/threonine/tyrosine kinases and oncoproteins… (More)
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2012
2012
The PIM kinase inhibitor, SGI-1776, was tested against the PPTP in vitro (1.0 nM-10 µM) and in vivo panels (148 mg/kg daily × 5… (More)
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Highly Cited
2011
Highly Cited
2011
Pim kinases are Ser/Thr kinases with multiple substrates that affect survival pathways. These proteins are overexpressed in acute… (More)
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Highly Cited
2009
Highly Cited
2009
Pim kinases are involved in B-cell development and are overexpressed in B-cell chronic lymphocytic leukemia (CLL). We… (More)
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Highly Cited
2009
Highly Cited
2009
The serine/threonine family of Pim kinases function as oncogenes and have been implicated in prostate cancer progression… (More)
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