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SFRP5 gene

Known as: SECRETED FRIZZLED-RELATED PROTEIN 5, SFRP5, secreted apoptosis related protein 3 
This gene may play a role in determining the polarity of photoreceptor cells in the retina.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Secreted frizzled-related proteins (SFRPs) are antagonists of the Wnt signaling pathway whose epigenetic downregulation have been… Expand
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Highly Cited
2014
Highly Cited
2014
In obesity, elevated fat mass and ectopic fat accumulation are associated with changes in adipokine secretion, which may link… Expand
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2013
2013
BACKGROUND Secreted frizzled-related protein 5 (Sfrp5), an endogenous inhibitor of wingless-type MMTV integration site family… Expand
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2013
2013
AIMS To detect plasma secreted frizzled-related protein (SFRP) 5 levels in Chinese healthy, obese and type 2 diabetes mellitus… Expand
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Highly Cited
2010
Highly Cited
2010
Oncogenic activation of the Wnt signaling pathway is common in cancers, but mutation of beta-catenin in ovarian cancer is rare… Expand
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Highly Cited
2008
Highly Cited
2008
Although mutation of APC or CTNNB1 (β-catenin) is rare in breast cancer, activation of Wnt signalling is nonetheless thought to… Expand
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Highly Cited
2008
Highly Cited
2008
Disruption of the Wnt pathway is thought to be crucial in the development of human cancer. Pathway inhibitory members of the… Expand
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Highly Cited
2008
Highly Cited
2008
BackgroundActivation of the Wnt signaling pathway is frequently observed in hepatocellular carcinoma (HCC), though mutation of… Expand
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Highly Cited
2007
Highly Cited
2007
Activation of Wnt signaling has been implicated in gastric tumorigenesis, although mutations in APC (adenomatous polyposis coli… Expand
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Highly Cited
2005
Highly Cited
2005
Curcumin (diferuloyl methane), the yellow-colored dietary pigment from the rhizomes of turmeric, has been recognized as a… Expand
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