SFRP2 gene

Known as: Secreted Frizzled-Related Protein 2 Gene, SDF-5, SECRETED FRIZZLED-RELATED PROTEIN 2 
This gene is involved in regulating cell growth and differentiation as a modulator of Wnt signaling.
National Institutes of Health

Papers overview

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2016
2016
Most tumors initially respond to cytotoxic treatments, but acquired resistance often follows. The tumor microenvironment (TME) is… (More)
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2010
2010
The aim of this study was to investigate the methylation of the SFRP2, P16, DAPK1, HIC1, and MGMT genes, as well as the mutation… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVES Aberrant activation of the Wnt/beta-catenin signaling pathway is common in human cancers, including cervical cancer… (More)
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Highly Cited
2008
Highly Cited
2008
Although mutation of APC or CTNNB1 (β-catenin) is rare in breast cancer, activation of Wnt signalling is nonetheless thought to… (More)
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2008
2008
AIM To investigate the feasibility of detecting hypermethylated secreted frizzled-related protein 2 (SFRP2) gene in fecal DNA as… (More)
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2008
2008
We have previously reported that expression of the Wnt antagonist genes SFRP1 and SFRP5 is frequently silenced by promoter… (More)
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Highly Cited
2007
Highly Cited
2007
The role of secreted frizzled-related protein (SFRP) genes in gastric cancer remains largely unknown. We determined the frequency… (More)
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Highly Cited
2007
Highly Cited
2007
UNLABELLED Using a moderate-sized cohort selected with extreme BMD (n = 344; absolute value BMD, 1.5-4.0), significant… (More)
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Highly Cited
2006
Highly Cited
2006
The soluble frizzled receptor protein (SFRP) family encodes antagonists of the WNT pathway, and silencing of these genes, through… (More)
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2003
2003
Despite their essential role in vertebrate development, the function of Pax proteins in gene regulation is not well understood… (More)
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