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SFRP2 gene

Known as: Secreted Frizzled-Related Protein 2 Gene, SDF-5, SECRETED FRIZZLED-RELATED PROTEIN 2 
This gene is involved in regulating cell growth and differentiation as a modulator of Wnt signaling.
National Institutes of Health

Related topics

Related topics

2 relations
Secreted Frizzled-Related Protein 2Signal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
SFRP2 modulates non‑small cell lung cancer A549 cell apoptosis and metastasis by regulating mitochondrial fission via Wnt pathways.
The secreted frizzled‑related protein 2 (SFRP2) has been reported to inhibit non‑small cell lung cancer (NSCLC) cell survival and… 
2017
2017
A pan-cancer analysis of secreted Frizzled-related proteins: re-examining their proposed tumour suppressive function
Secreted frizzled-related proteins (SFRPs), containing five family members (SFRPs 1–5) are putative extracellular Wnt inhibitors… 
2014
2014
Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer
Aberrant DNA methylation could potentially serve as a biomarker for colorectal neoplasms. In this study, we assessed the… 
2011
2011
Epigenetic fingerprint in endometrial carcinogenesis: The hypothesis of a uterine field cancerization
Transcriptional silencing by CpG island hypermethylation plays a critical role in endometrial carcinogenesis. In a collection of… 
2010
2010
Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.
It is well known that approximately 90% of colorectal cancer (CRC) cases originate from the constitutive activation of the… 
2009
2009
Imprinting of tumor-suppressor genes in human placenta
Transcriptional deregulation in cancer has been shown to be associated with epigenetic alterations, in particular to tumor… 
Highly Cited
2008
Highly Cited
2008
Epigenetic inactivation of secreted Frizzled‐related proteins in acute myeloid leukaemia
The Wnt signalling pathway has a key function in stem cell maintenance and differentiation of haematopoietic progenitors… 
2005
2005
Comparative genomics on SFRP2 orthologs.
SFRP1, SFRP2, SFRP3, SFRP4, SFRP5, DKK1, DKK2, DKK3, DKK4, and WIF1 are soluble modulators of WNT signaling. SFRP2 gene at human… 
Highly Cited
2004
Highly Cited
2004
Autocrine/Paracrine Secreted Frizzled-related Protein 2 Induces Cellular Resistance to Apoptosis
Abnormal regulation of apoptosis and cell proliferation is thought to be involved in tumor formation. The secreted Frizzled… 
2004
2004
SFRP2 expression in rabbit myogenic progenitor cells and in adult skeletal muscles
Satellite cells derived from fast- and slow-twitch muscles have different properties in culture. We have used the differential… 
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