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SFN wt Allele
Known as:
Stratifin wt Allele
, HME1
, 14-3-3 Sigma Gene
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Human SFN wild-type allele is located in the vicinity of 1p36.11 and is approximately 1 kb in length. This allele, which encodes 14-3-3 protein sigma…
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National Institutes of Health
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Related topics
Related topics
4 relations
1p35.3
Cell Cycle Control
EFP Cell Cycle Pathway
Negative Regulation of Cell Cycle
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Inactivation of 14‐3‐3 σ by promoter methylation correlates with metastasis in nasopharyngeal carcinoma
B. Yi
,
Shuang-xiang Tan
,
+10 authors
Zhi-Qiang Xiao
Journal of cellular biochemistry
2009
Corpus ID: 206016315
14‐3‐3 σ, the downstream target of p53, is a negative regulator of cell cycle G2‐M phase checkpoint in response to DNA damage…
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Highly Cited
2008
Highly Cited
2008
Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells.
D. Junk
,
L. Vrba
,
G. Watts
,
M. Oshiro
,
Jesse D. Martinez
,
B. Futscher
Neoplasia
2008
Corpus ID: 22504734
Aberrations of p53 occur in most, if not all, human cancers. In breast cancer, p53 mutation is the most common genetic defect…
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Highly Cited
2006
Highly Cited
2006
Molecular evolution of the 14-3-3 protein family
Wenfu Wang
,
D. Shakes
Journal of Molecular Evolution
2006
Corpus ID: 22211345
Members of the highly conserved and ubiquitous 14-3-3 protein family modulate a wide variety of cellular processes. To determine…
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2006
2006
Promoter hypermethylation of the 14-3-3 sigma, SYK and CAGE-1 genes is related to the various phenotypes of urinary bladder carcinomas and associated with progression of transitional cell carcinomas.
E. Kunze
,
Maike Wendt
,
T. Schlott
International journal of molecular medicine
2006
Corpus ID: 19850614
To explore the significance of epigenetic mechanisms in urinary bladder carcinogenesis mediated by methylation of cytosine in CpG…
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Highly Cited
2004
Highly Cited
2004
Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases.
T. Hagemann
,
S. Robinson
,
M. Schulz
,
L. Trümper
,
F. Balkwill
,
C. Binder
Carcinogenesis
2004
Corpus ID: 15546090
Apart from the neoplastic cells, malignant tumours consist of the extracellular matrix (ECM) and normal cells, in particular…
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Highly Cited
2004
Highly Cited
2004
Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: its correlation with aberrant DNA methylation.
J. Akahira
,
Youko Sugihashi
,
+9 authors
N. Yaegashi
Clinical cancer research : an official journal of…
2004
Corpus ID: 16671095
PURPOSE In this study, we examined the promoter methylation status and expression of 14-3-3 sigma and evaluated its clinical…
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Highly Cited
2004
Highly Cited
2004
Expression and methylation status of 14-3-3 sigma gene can characterize the different histological features of ovarian cancer.
M. Kaneuchi
,
M. Sasaki
,
+7 authors
R. Dahiya
Biochemical and biophysical research…
2004
Corpus ID: 2083388
Highly Cited
2002
Highly Cited
2002
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell…
Hyangkyu Lee
,
David S. Park
,
B. Razani
,
R. Russell
,
R. Pestell
,
M. Lisanti
The American journal of pathology
2002
Corpus ID: 36075990
Highly Cited
2000
Highly Cited
2000
Inactivation of the 14-3-3 sigma gene is associated with 5' CpG island hypermethylation in human cancers.
H. Suzuki
,
F. Itoh
,
M. Toyota
,
T. Kikuchi
,
H. Kakiuchi
,
K. Imai
Cancer research
2000
Corpus ID: 35768935
The cell cycle checkpoint plays an important role in maintaining the integrity of cells. Recently, one of the 14-3-3 protein…
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Highly Cited
1992
Highly Cited
1992
Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells.
G. L. Prasad
,
E. Valverius
,
E. McDuffie
,
H. Cooper
Cell growth & differentiation : the molecular…
1992
Corpus ID: 15660365
A full-length complementary DNA clone from a normal human mammary epithelial cell (strain 184) encoding a 25-kilodalton protein…
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