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SF 2575

Known as: Benzoic acid, 2-hydroxy-, 3-(aminocarbonyl)-8-(2,6-dideoxy-4-O-(2-methyl-1-oxo-2-butenyl)-beta-D-arabino-hexopyranosyl)-1,4,4a,6,11,11a,12,12a-octahydro-2,5,7-trihydroxy-4a,11-dimethoxy-11-methyl-4,6-dioxo-1-naphthacenyl ester, (1R-(1a,4aalpha,11.beta)), SF-2575, SF2575 
National Institutes of Health

Papers overview

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2011
2011
Structural and Biochemical Characterization of the Salicylyl-acyltranferase SsfX3 from a Tetracycline Biosynthetic Pathway*♦
Background: SsfX3 is an acyltransferase that can acylate tetracycline-like molecules at C-4. Results: Crystal structure showed… 
2011
2011
Characterization of the Biosynthetic Pathway of Anticancer Tetracycline SF2575
Highly Cited
2009
Highly Cited
2009
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.
SF2575 1 is a tetracycline polyketide produced by Streptomyces sp. SF2575 and displays exceptionally potent anticancer activity… 
1992
1992
A new tetracycline antibiotic with antitumor activity. II. The structural elucidation of SF2575.
The structure of a new antitumor antibiotic SF2575, has been determined by spectroscopic analyses of the antibiotic and its… 
1992
1992
A new tetracycline antibiotic with antitumor activity. I. Taxonomy and fermentation of the producing strain, isolation and characterization of SF2575.
A new antitumor antibiotic SF2575 has been isolated from a culture filtrate of Streptomyces sp. SF2575. The molecular formula was… 
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