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SF 2575

Known as: Benzoic acid, 2-hydroxy-, 3-(aminocarbonyl)-8-(2,6-dideoxy-4-O-(2-methyl-1-oxo-2-butenyl)-beta-D-arabino-hexopyranosyl)-1,4,4a,6,11,11a,12,12a-octahydro-2,5,7-trihydroxy-4a,11-dimethoxy-11-methyl-4,6-dioxo-1-naphthacenyl ester, (1R-(1a,4aalpha,11.beta)), SF-2575, SF2575 
 
National Institutes of Health

Papers overview

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2011
2011
Structural and Biochemical Characterization of the Salicylyl-acyltranferase SsfX3 from a Tetracycline Biosynthetic Pathway*♦
Background: SsfX3 is an acyltransferase that can acylate tetracycline-like molecules at C-4. Results: Crystal structure showed… Expand
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2011
2011
Characterization of the Biosynthetic Pathway of Anticancer Tetracycline SF2575
 
Highly Cited
2009
Highly Cited
2009
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.
SF2575 1 is a tetracycline polyketide produced by Streptomyces sp. SF2575 and displays exceptionally potent anticancer activity… Expand
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1992
1992
A new tetracycline antibiotic with antitumor activity. II. The structural elucidation of SF2575.
The structure of a new antitumor antibiotic SF2575, has been determined by spectroscopic analyses of the antibiotic and its… Expand
1992
1992
A new tetracycline antibiotic with antitumor activity. I. Taxonomy and fermentation of the producing strain, isolation and characterization of SF2575.
A new antitumor antibiotic SF2575 has been isolated from a culture filtrate of Streptomyces sp. SF2575. The molecular formula was… Expand
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