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SERPINB7 gene

Known as: MEGSIN, SERPINB7, SERPIN PEPTIDASE INHIBITOR, CLADE B (OVALBUMIN), MEMBER 7 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Delivery of megsin siRNA plasmid reveals therapeutic potential against diabetic nephropathy by down-regulating p27(kip1) level.
BACKGROUND Diabetic nephropathy is a complex disease with poor outcomes, and our current treatment measures are limited. It is… 
2011
2011
Overexpression of megsin induces mesangial cell proliferation and excretion of type IV collagen in vitro.
2007
2007
Megsin gene: its genomic analysis, pathobiological functions, and therapeutic perspectives.
It is critical to uncover genes specifically expressed in individual cell types for further understanding of cell biology and… 
2007
2007
Establishment of a sandwich ELISA for human megsin, a kidney-specific serine protease inhibitor.
BACKGROUND We previously identified a novel serine protease inhibitor (serpin), megsin, which is predominantly expressed in the… 
2006
2006
A family-based association study of megsin A23167G polymorphism with susceptibility and progression of IgA nephropathy in a Chinese population.
AIMS To investigate the association of megsin A23167G polymorphism with susceptibility and progression of IgA nephropathy in… 
2006
2006
A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies).
2006
2006
A Study of Megsin Gene C25663G Polymorphism with IgA Nephropathy
Objective:To investigate the relationship of Megsin gene C25663G polymorphism and IgA nephropathy in Chinese Han population… 
Review
2006
Review
2006
[Association of single nucleotide polymorphism of megsin gene with IgA nephropathy].
OBJECTIVE To investigate whether the single nucleotide polymorphisms (SNPs) in the gene of megsin, a novel serine protease… 
Review
2005
Review
2005
Synergistic Contributions of Carbonyl Stress and Megsin in Diabetic Nephropathy
Abstract: Diabetic nephropathy is the most common cause of end‐stage renal failure. The primary glomerular changes in diabetic… 
2004
2004
Accelerated Glomerular Injury in Hemi-Nephrectomized Transgenic Mice of Mesangial Cell-Predominant Serpin, Megsin
Mesangial cells play a critical role in the maintenance of normal glomerular functions such as matrix remodeling and immune… 
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