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SERPINB5 gene

Known as: MASPIN, PI5, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 Gene 
This gene is involved in DNA methylation and plays a role in tumor suppression.
National Institutes of Health

Related topics

Related topics

7 relations
Cell AdhesionCell-Matrix JunctionLigand BindingMetastasis Suppression

Narrower (1)

SERPINB5 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Protease activated receptor-1 inhibits the Maspin tumor-suppressor gene to determine the melanoma metastatic phenotype
The thrombin receptor protease activated receptor-1 (PAR-1) is overexpressed in metastatic melanoma cell lines and tumor… 
Highly Cited
2006
Highly Cited
2006
Maspin expression and localization impact on angiogenesis and prognosis in ovarian cancer.
Highly Cited
2006
Highly Cited
2006
Epigenetic regulation of maspin expression in human ovarian carcinoma cells.
Highly Cited
2004
Highly Cited
2004
Bax Mediates the Apoptosis-Sensitizing Effect of Maspin
Maspin, a serine protease inhibitor (serpin), can suppress tumor growth and metastasis in vivo and tumor cell motility and… 
2004
2004
Maspin expression in normal and neoplastic salivary gland.
BACKGROUND Maspin inhibits cell motility, invasion and metastasis. Loss or reduction in maspin expression has been associated… 
Highly Cited
2004
Highly Cited
2004
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
Highly Cited
2003
Highly Cited
2003
Maspin – the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer – is strongly expressed in preneoplastic bronchial lesions
Maspin, SCCA1/2 and hurpin were identified by cDNA microarray analyses as dramatically differentially expressed transcripts in… 
Highly Cited
2002
Highly Cited
2002
Hypermethylation and histone deacetylation lead to silencing of the maspin gene in human breast cancer.
Highly Cited
2001
Highly Cited
2001
Maspin expression in stage I and II oral tongue squamous cell carcinoma
A relatively high failure rate in the therapy of patients with early oral tongue squamous cell carcinomas (SCCs) is evidenced by… 
1999
1999
Use of reverse-transcriptase polymerase chain reaction (RT-PCR) for carcinoembryonic antigen, cytokeratin 19, and maspin in the detection of tumor cells in leukapheresis products from patients with…
This study evaluates the role of reverse-transcriptase polymerase chain reaction (RT-PCR) assay for carcinoembryonic antigen (CEA… 
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