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SEMA4D protein, human

Known as: M-Sema-G, C9orf164, CD100 antigen, human 
Semaphorin-4D (862 aa, ~96 kDa) is encoded by the human SEMA4D gene. This protein is involved in both axonal growth cone guidance in the developing… Expand
National Institutes of Health

Papers overview

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2016
2016
Osteoporosis is a prominent disorder affecting over 200 million people worldwide. Recently, semaphorins have been implicated in… Expand
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2016
2016
Semaphorins and their receptors plexins have diverse roles in many cancers affecting tumour growth, metastasis and angiogenesis… Expand
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Highly Cited
2015
Highly Cited
2015
Semaphorins have been recently targeted as new molecules directly implicated in the cell‐cell communication that occurs between… Expand
2014
2014
BACKGROUND Hypoxia promotes tumor angiogenesis and hypoxia-inducible factor-1 alpha (HIF-1α) plays a pivotal role in this process… Expand
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2013
2013
BackgroundPancreatic cancer is one of the most aggressive human malignancies with a extremely low 5-year survival rate. Hence… Expand
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2012
2012
Summary Signaling through the semaphorin 4D (Sema4D) receptor plexin-B1 is modulated by its interaction with tyrosine kinases… Expand
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2012
2012
Semaphorin4D (SEMA4D) has been regarded as an important protein in tumor angiogenesis, though originally identified in… Expand
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Highly Cited
2008
Highly Cited
2008
In mammals, reproduction is dependent on specific neurons secreting the neuropeptide gonadotropin hormone–releasing hormone-1… Expand
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Review
2007
Review
2007
The neuropilins were originally characterized as cell membrane receptors that bind axon guidance factors belonging to the class-3… Expand
Highly Cited
2002
Highly Cited
2002
The small GTPase Rac has been implicated in growth cone guidance mediated by semaphorins and their receptors. Here we demonstrate… Expand