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SEMA4D protein, human

Known as: M-Sema-G, C9orf164, CD100 antigen, human 
Semaphorin-4D (862 aa, ~96 kDa) is encoded by the human SEMA4D gene. This protein is involved in both axonal growth cone guidance in the developing… Expand
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

CD100 antigen
SEMA4D geneSignal TransductionSignaling Pathway Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Bone scaffolds loaded with siRNA-Semaphorin4d for the treatment of osteoporosis related bone defects
Osteoporosis is a prominent disorder affecting over 200 million people worldwide. Recently, semaphorins have been implicated in… Expand
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2016
2016
The combined expression of Semaphorin4D and PlexinB1 predicts disease recurrence in colorectal cancer
BackgroundBinding to Sema4D and PlexinB1 induce angiogenesis and invasive growth in colorectal cancer (CRC). The expression of… Expand
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2015
2015
Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment.
OBJECTIVE The evaluation of circulating semaphorin-4D (sema4D) and plexin-B1 in postmenopausal women with low bone mass and the… Expand
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2015
2015
Anabolic bone formation via a site-specific bone-targeting delivery system by interfering with semaphorin 4D expression.
Semaphorins have been recently targeted as new molecules directly implicated in the cell-cell communication that occurs between… Expand
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2014
2014
B-plexins control microtubule dynamics and dendrite morphology of hippocampal neurons.
Semaphorins and their receptors plexins are implicated in various processes in the nervous system, but how B-plexins regulate the… Expand
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2014
2014
Enhanced potency of the metalloprotease inhibitor TAPI-2 by multivalent display.
Metalloproteases regulate a vast array of critical cellular processes such as proliferation, migration, repair, and invasion… Expand
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2013
2013
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells
BackgroundPancreatic cancer is one of the most aggressive human malignancies with a extremely low 5-year survival rate. Hence… Expand
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2008
2008
Semaphorin 4D regulates gonadotropin hormone–releasing hormone-1 neuronal migration through PlexinB1–Met complex
In mammals, reproduction is dependent on specific neurons secreting the neuropeptide gonadotropin hormone-releasing hormone-1… Expand
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Review
2007
Review
2007
Semaphorin signaling in vascular and tumor biology.
The neuropilins were originally characterized as cell membrane receptors that bind axon guidance factors belonging to the class-3… Expand
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Highly Cited
2002
Highly Cited
2002
The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding.
The small GTPase Rac has been implicated in growth cone guidance mediated by semaphorins and their receptors. Here we demonstrate… Expand
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