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SEMA4D protein, human
Known as:
M-Sema-G
, C9orf164
, CD100 antigen, human
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Semaphorin-4D (862 aa, ~96 kDa) is encoded by the human SEMA4D gene. This protein is involved in both axonal growth cone guidance in the developing…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (1)
CD100 antigen
SEMA4D gene
Signal Transduction
Signaling Pathway Gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Plexin-B1 signalling promotes androgen receptor translocation to the nucleus
M. Williamson
,
P. D. Winter
,
J. Masters
Oncogene
2016
Corpus ID: 25187518
Semaphorins and their receptors plexins have diverse roles in many cancers affecting tumour growth, metastasis and angiogenesis…
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Highly Cited
2015
Highly Cited
2015
Anabolic Bone Formation Via a Site‐Specific Bone‐Targeting Delivery System by Interfering With Semaphorin 4d Expression
Yufeng Zhang
,
Lingfei Wei
,
R. Miron
,
B. Shi
,
Z. Bian
Journal of Bone and Mineral Research
2015
Corpus ID: 21537509
Semaphorins have been recently targeted as new molecules directly implicated in the cell‐cell communication that occurs between…
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2014
2014
B-plexins control microtubule dynamics and dendrite morphology of hippocampal neurons.
Piret Laht
,
Maarja Otsus
,
J. Remm
,
A. Veske
Experimental Cell Research
2014
Corpus ID: 24214586
2014
2014
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells
Xing-dong Xu
,
Lan Yang
,
+6 authors
C. Cao
BMC Cancer
2014
Corpus ID: 52817686
BackgroundPancreatic cancer is one of the most aggressive human malignancies with a extremely low 5-year survival rate. Hence…
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2012
2012
Over-Expression of Semaphorin4D, Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor Is Related to Poor Prognosis in Ovarian Epithelial Cancer
Ying Chen
,
Lei Zhang
,
Yi Pan
,
X. Ren
,
Q. Hao
International Journal of Molecular Sciences
2012
Corpus ID: 249326
Semaphorin4D (SEMA4D) has been regarded as an important protein in tumor angiogenesis, though originally identified in…
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2012
2012
Grb2 mediates semaphorin-4D-dependent RhoA inactivation
Tianliang Sun
,
R. Krishnan
,
J. Swiercz
Journal of Cell Science
2012
Corpus ID: 38045819
Summary Signaling through the semaphorin 4D (Sema4D) receptor plexin-B1 is modulated by its interaction with tyrosine kinases…
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Highly Cited
2008
Highly Cited
2008
Semaphorin 4D regulates gonadotropin hormone–releasing hormone-1 neuronal migration through PlexinB1–Met complex
P. Giacobini
,
A. Messina
,
+6 authors
A. Fasolo
Journal of Cell Biology
2008
Corpus ID: 15781006
In mammals, reproduction is dependent on specific neurons secreting the neuropeptide gonadotropin hormone–releasing hormone-1…
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Review
2007
Review
2007
Semaphorin signaling in vascular and tumor biology.
G. Neufeld
,
Tali Lange
,
A. Varshavsky
,
O. Kessler
Advances in Experimental Medicine and Biology
2007
Corpus ID: 22692630
The neuropilins were originally characterized as cell membrane receptors that bind axon guidance factors belonging to the class-3…
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Review
2005
Review
2005
Semaphorins in cancer.
G. Neufeld
,
N. Shraga-Heled
,
Tali Lange
,
N. Guttmann-Raviv
,
Y. Herzog
,
O. Kessler
Frontiers in Bioscience
2005
Corpus ID: 41950098
The semaphorins are the products of a large family of genes currently containing more than 30 members. These genes are divided…
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Highly Cited
2002
Highly Cited
2002
The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding.
H. Vikis
,
Weiquan Li
,
K. Guan
Genes & Development
2002
Corpus ID: 40058019
The small GTPase Rac has been implicated in growth cone guidance mediated by semaphorins and their receptors. Here we demonstrate…
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