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SEMA4D gene

Known as: Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (semaphorin) 4D Gene, SEMAJ, COLL4 
This gene is involved in both cell-cell signaling and axonal growth cone guidance.
National Institutes of Health

Related topics

Related topics

3 relations
CD100 antigenSEMA4D protein, humanSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Association between prognosis and SEMA4D/Plexin-B1 expression in various malignancies
Introduction: SEMA4D and its high affinity receptor Plexin-B1 showed a promising prognosis prediction for carcinoma patients in… 
2019
2019
Upregulation of IFN-β induced by Sema4D-dependent partial Erk1/2 inhibition promotes NO production in microglia.
2017
2017
Genome‐wide analysis identifies an african‐specific variant in SEMA4D associated with body mass index
The prevalence of obesity varies between ethnic groups. No genome‐wide association study (GWAS) for body mass index (BMI) has… 
2017
2017
Identification and Evaluation of New Immunoregulatory Genes in Mesenchymal Stromal Cells of Different Origins: Comparison of Normal and Inflammatory Conditions
Background Mesenchymal stromal cells (MSCs) possess potent immunomodulatory properties that increase their value as a cell-based… 
2016
2016
The Semaphorin 4D‐RhoA‐Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination With Cell Polarization During Ameloblast Differentiation
During tooth development, oral epithelial cells differentiate into ameloblasts in order to form the most mineralized tissue in… 
2014
2014
[Correlation and clinical significance of expressions of HIF-1α and Sema4D in colorectal carcinoma tissues].
OBJECTIVE To compare the expressions of hypoxia-inducible factor 1 alpha(HIF-1α) and Semaphorin 4D(Sema4D) in colorectal… 
2013
2013
Overexpression of Semaphorin 4 D Indicates Poor Prognosis and Prompts Monocyte Differentiation toward M 2 Macrophages in Epithelial Ovarian Cancer
Epithelial ovarian cancer (EOC) is the leading killer among all gynecological malignancies (Siegel et al., 2012). Over 70% of EOC… 
2013
2013
Segmental copy number loss in the region of Semaphorin 4D gene in patients with acetabular dysplasia
Acetabular dysplasia (AD) appears to be a multi‐factorial disease, which may involve both genetic and environmental factors and… 
2010
2010
Candidate gene analysis of semaphorins in patients with Alzheimer’s disease
Semaphorins of the SemaIV family are expressed in neurons and decreased in brains from patients with Alzheimer’s disease (AD… 
2009
2009
Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior
Background: Sema4D/CD100 is a type of class 4 semaphorin, exhibiting crucial rôles in growth cone guidance in developing neurons… 
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