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SEMA4D gene

Known as: Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (semaphorin) 4D Gene, SEMAJ, COLL4 
This gene is involved in both cell-cell signaling and axonal growth cone guidance.
National Institutes of Health

Related topics

Related topics

3 relations
CD100 antigenSEMA4D protein, humanSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis
Semaphorin 4D (Sema4D; CD100) is a transmembrane homodimer 150-kDa glycoprotein member of the Semaphorin family. Semaphorins were… 
Review
2015
Review
2015
Plasmodium spp.: an experimental study on vertebrate host susceptibility to avian malaria.
2015
2015
Generation and preclinical characterization of an antibody specific for SEMA4D
Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and… 
2012
2012
Sema4D as an inhibitory regulator in oligodendrocyte development
2011
2011
Semaphorin-plexin signalling genes associated with human breast tumourigenesis.
Highly Cited
2010
Highly Cited
2010
Structural basis of semaphorin–plexin signalling
Cell-cell signalling of semaphorin ligands through interaction with plexin receptors is important for the homeostasis and… 
Highly Cited
2010
Highly Cited
2010
Structural basis for semaphorin signalling through the plexin receptor
Semaphorins and their receptor plexins constitute a pleiotropic cell-signalling system that is used in a wide variety of… 
Highly Cited
2009
Highly Cited
2009
Integrative Physiology/Experimental Medicine Disruption of SEMA4D Ameliorates Platelet Hypersensitivity in Dyslipidemia and Confers Protection Against the Development of Atherosclerosis
Objective—In dyslipidemic states, platelets become hyperreactive, secreting molecules that promote atherosclerosis. We have shown… 
Highly Cited
2003
Highly Cited
2003
The Transmembrane Semaphorin Sema4D/CD100, an Inhibitor of Axonal Growth, Is Expressed on Oligodendrocytes and Upregulated after CNS Lesion
Semaphorins are a family of secreted and membrane-bound proteins, known to regulate axonal pathfinding. Sema4D, also called CD100… 
Highly Cited
1996
Highly Cited
1996
CD100 is associated with CD45 at the surface of human T lymphocytes. Role in T cell homotypic adhesion.
CD100 is a 150-kDa human surface glycoprotein implicated in T cell activation. Using BB18 and BD16 mAbs to two discrete epitopes… 
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