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SEMA3E gene

Known as: SEMAH, M-SemaK, SEMAPHORIN 3E 
This gene plays a role in intercellular communication. It is also putatively involved in both neurogenesis and vasculogenesis.
National Institutes of Health

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Class 3 SemaphorinsIntercellular Communication ProcessSEMA3E protein, humanSema3e protein, mouse

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SEMA3E wt Allele

Papers overview

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Highly Cited
2015
Highly Cited
2015
Dysfunctional SEMA3E signaling underlies gonadotropin-releasing hormone neuron deficiency in Kallmann syndrome.
Individuals with an inherited deficiency in gonadotropin-releasing hormone (GnRH) have impaired sexual reproduction. Previous… 
Highly Cited
2013
Highly Cited
2013
Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity.
Highly Cited
2012
Highly Cited
2012
Semaphorin-3D and Semaphorin-3E Inhibit the Development of Tumors from Glioblastoma Cells Implanted in the Cortex of the Brain
Class-3 semaphorins are secreted axon guidance factors. Some of these semaphorins have recently been characterized as suppressors… 
Highly Cited
2011
Highly Cited
2011
Sema3E/Plexin-D1 Mediated Epithelial-to-Mesenchymal Transition in Ovarian Endometrioid Cancer
Cancer cells often employ developmental cues for advantageous growth and metastasis. Here, we report that an axon guidance… 
2010
2010
The Aesthetics of Public Visibility: Alevi Semah and the Paradoxes of Pluralism in Turkey
Efforts to theorize pluralism have often explored the challenges posed by the public visibility of ethnic, linguistic, and… 
Highly Cited
2009
Highly Cited
2009
Specificity of sensory–motor connections encoded by Sema3e–Plxnd1 recognition
Spinal reflexes are mediated by synaptic connections between sensory afferents and motor neurons. The organization of these… 
Highly Cited
2008
Highly Cited
2008
Successful Inhibition of Tumor Development by Specific Class-3 Semaphorins Is Associated with Expression of Appropriate Semaphorin Receptors by Tumor Cells
The class-3 semaphorins (sema3s) include seven family members. Six of them bind to neuropilin-1 (np1) or neuropilin-2 (np2… 
Highly Cited
2005
Highly Cited
2005
Proteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasis.
We have previously shown that the expression of a semaphorin, known as a repelling cue in axon guidance, Sema3E, correlates with… 
Highly Cited
2004
Highly Cited
2004
SEMA3E mutation in a patient with CHARGE syndrome
CHARGE association (MIM 214800) is a sporadic disorder, characterised by coloboma of the eye, choanal atresia, cranial nerve… 
Highly Cited
2001
Highly Cited
2001
Age-Dependent Effects of Secreted Semaphorins 3A, 3F, and 3E on Developing Hippocampal Axons: In Vitro Effects and Phenotype of Semaphorin 3A (−/−) Mice
We studied the role of Semaphorins in the formation of hippocampal connections at embryonic and early postnatal stages. We show… 
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