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SECISBP2 gene

Known as: SECIS-BINDING PROTEIN 2, SECISBP2, SBP2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations
Recoding of UGA codons as selenocysteine (Sec) codons in selenoproteins depends on a selenocysteine insertion sequence (SECIS) in… 
2018
2018
Selenium‐sensitive miRNA‐181a‐5p targeting SBP2 regulates selenoproteins expression in cartilage
Selenium (Se) deficiency brings about defects in the biosynthesis of several selenoproteins and has been associated with aberrant… 
2014
2014
The SBP2 protein central to selenoprotein synthesis contacts the human ribosome at expansion segment 7L of the 28S rRNA
Selenoprotein biogenesis depends upon SBP2, a protein that binds the SECIS stem–loop and the 60S subunit of the ribosome. This… 
2012
2012
Selenocysteine Insertion Sequence (SECIS)-binding Protein 2 Alters Conformational Dynamics of Residues Involved in tRNA Accommodation in 80 S Ribosomes*
Background: Selenocysteine incorporation requires unique translation factors that interact with the ribosome. Results: SECIS… 
2012
2012
Strength of relationships of the pulse wave velocity and central hemodynamic indices with the serum N-terminal fragment B-type natriuretic peptide levels in men: a worksite cohort study.
BACKGROUND It has not been fully clarified as to which marker related to arterial stiffness or central hemodynamics might be most… 
Review
2011
Review
2011
Inherited defects of thyroid hormone metabolism.
2009
2009
A short motif in Drosophila SECIS Binding Protein 2 provides differential binding affinity to SECIS RNA hairpins
Selenoproteins contain the amino acid selenocysteine which is encoded by a UGA Sec codon. Recoding UGA Sec requires a complex… 
2007
2007
The L7Ae RNA Binding Motif Is a Multifunctional Domain Required for the Ribosome-Dependent Sec Incorporation Activity of Sec Insertion Sequence Binding Protein 2
ABSTRACT The decoding of specific UGA codons as selenocysteine is specified by the Sec insertion sequence (SECIS) element… 
2005
2005
Knowing when not to stop
  • M. Berry
  • Nature Structural &Molecular Biology
  • 2005
  • Corpus ID: 20239778
A recent study reveals that the eukaryotic ribosomal protein L30 binds to the selenocysteine recoding RNA element and may… 
1994
1994
The rat growth hormone proximal silencer contains a novel DNA-binding site for multiple nuclear proteins that represses basal promoter activity.
Cell-type-specific expression of the rat growth hormone (rGH) gene is determined by the interaction of both positive as well as… 
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