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SEC62 gene

Known as: TRANSLOCATION PROTEIN 1, DROSOPHILA, HOMOLOG OF, HTP1, Dtrp1 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Structure of the posttranslational Sec protein-translocation channel complex from yeast
Posttranslational translocon architecture About a third of proteins are transported into endoplasmic reticulum by the universally… 
Highly Cited
2019
Highly Cited
2019
MiR-4429 prevented gastric cancer progression through targeting METTL3 to inhibit m6A-caused stabilization of SEC62.
2019
2019
Sec62 promotes early recurrence of hepatocellular carcinoma through activating integrinα/CAV1 signalling
Postsurgical recurrence within 2 years is the major cause of poor survival of hepatocellular carcinoma (HCC) patients. However… 
2017
2017
Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?
ABSTRACT Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently… 
Highly Cited
2015
Highly Cited
2015
Cotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events.
2013
2013
The Signal Sequence Influences Post-Translational ER Translocation at Distinct Stages
The metazoan Sec61 translocon transports polypeptides into and across the membrane of the endoplasmic reticulum via two major… 
Highly Cited
2012
Highly Cited
2012
Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells
Co-translational transport of polypeptides into the endoplasmic reticulum (ER) involves the Sec61 channel and additional… 
Highly Cited
2012
Highly Cited
2012
Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection
BackgroundHepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Frequent tumor recurrence after surgery is… 
2011
2011
Sec62 protein level is crucial for the ER stress tolerance of prostate cancer
We previously reported that over‐expression of the SEC62 gene is a widespread phenomenon in prostate cancer. Since the use of… 
2002
2002
A putative novel nuclear-encoded subunit of the cytochrome c oxidase complex in trypanosomatids.
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