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SDHD protein, human

Known as: Mitochondrial Complex II, Respiratory Complex II, succinate dehydrogenase complex, subunit D, integral membrane protein, human 
A heterotetrameric enzyme complex found in the inner mitochondrial membrane. This protein complex catalyzes the oxidation of succinate and reduction… 
National Institutes of Health

Related topics

Related topics

16 relations
Cell RespirationInner mitochondrial membraneIonophore activityOxidation-Reduction

Broader (2)

Electron Transport Complex IISuccinate Dehydrogenase

Papers overview

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Highly Cited
2016
Highly Cited
2016
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
Highly Cited
2016
Highly Cited
2016
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Highly Cited
2014
Highly Cited
2014
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then restored, and underlies many… 
Highly Cited
2012
Highly Cited
2012
Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions*
Background: Complex II is not considered a significant contributor to mitochondrial ROS production. Results: Complex II generates… 
Highly Cited
2005
Highly Cited
2005
Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II
Highly Cited
2003
Highly Cited
2003
Architecture of Succinate Dehydrogenase and Reactive Oxygen Species Generation
The structure of Escherichia colisuccinate dehydrogenase (SQR), analogous to the mitochondrial respiratory complex II, has been… 
Highly Cited
1998
Highly Cited
1998
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
Much attention has focused on the aetiology of oxidative damagein cellular and organismal ageing. Especially toxic arethe… 
Highly Cited
1995
Highly Cited
1995
Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency
We now report a mutation in the nuclear–encoded flavoprotein (Fp) subunit gene of the succinate dehydrogenase (SDH) in two… 
Highly Cited
1976
Highly Cited
1976
Role of ubiquinone in the mitochondrial generation of hydrogen peroxide.
Antimycin-inhibited bovine heart submitochondrial particles generate O2- and H2O2 with succinate as electron donor. H2O2… 
Highly Cited
1973
Highly Cited
1973
Peroxisomal and Mitochondrial Defects in the Cerebro-Hepato-Renal Syndrome
The cerebro-hepato-renal syndrome is a rare familial malady with cerebral, renal, and skeletal abnormalities, severe hypotonia… 
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