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SDC3 protein, human

Known as: N-Syndecan, Syndecan Neural Type, SYND3 
Syndecan-3 (442 aa, ~45 kDa) is encoded by the human SDC3 gene. This protein is involved in glycosaminoglycan metabolism.
National Institutes of Health

Related topics

Related topics

10 relations
Cell AdhesionCell-Matrix JunctionClusters of differentiationCytoskeletal Modeling
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Broader (1)

Syndecan-3

Papers overview

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Highly Cited
2010
Highly Cited
2010
Syndecan-3 and Notch cooperate in regulating adult myogenesis
Syndecan-3 is required for Notch processing by ADAM17/TACe and therefore regulates proliferation and viability of muscle… Expand
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2007
2007
Binding of human papilloma virus L1 virus-like particles to dendritic cells is mediated through heparan sulfates and induces immune activation.
Immunization using human papilloma virus (HPV)-L1 virus-like particles (VLPs) induces a robust and effective immune response… Expand
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Highly Cited
2006
Highly Cited
2006
Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be…
Agouti-related protein (AGRP) plays a key role in energy homeostasis. The carboxyl-terminal domain of AGRP acts as an endogenous… Expand
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Highly Cited
2006
Highly Cited
2006
Heparan sulfate proteoglycans including syndecan-3 modulate BMP activity during limb cartilage differentiation.
Bone morphogenetic proteins (BMPs) are involved in multiple aspects of limb development including regulation of cartilage… Expand
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Highly Cited
2004
Highly Cited
2004
Heparan sulfate proteoglycans are increased during skeletal muscle regeneration: requirement of syndecan-3 for successful fiber formation
Skeletal muscle regeneration is a highly complex and regulated process that involves muscle precursor proliferation and… Expand
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Highly Cited
2004
Highly Cited
2004
Mice lacking the syndecan-3 gene are resistant to diet-induced obesity.
The accurate matching of caloric intake to caloric expenditure involves a complex system of peripheral signals and numerous CNS… Expand
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Highly Cited
2001
Highly Cited
2001
Syndecan-3 and syndecan-4 specifically mark skeletal muscle satellite cells and are implicated in satellite cell maintenance and muscle regeneration.
Myogenesis in the embryo and the adult mammal consists of a highly organized and regulated sequence of cellular processes to form… Expand
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Highly Cited
2001
Highly Cited
2001
Transgenic Expression of Syndecan-1 Uncovers a Physiological Control of Feeding Behavior by Syndecan-3
Transgenic expression in the hypothalamus of syndecan-1, a cell surface heparan sulfate proteoglycan (HSPG) and modulator of… Expand
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1999
1999
Antisense Inhibition of Syndecan-3 Expression during Skeletal Muscle Differentiation Accelerates Myogenesis through a Basic Fibroblast Growth Factor-dependent Mechanism*
Syndecan-3 is a member of a family of transmembrane proteoglycans that posses highly homologous cytoplasmic and transmembrane… Expand
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1995
1995
Syndecan-3, tenascin-C, and the development of cartilaginous skeletal elements and joints in chick limbs.
The mechanisms by which the early limb cell condensations and interzone mesenchyme give rise to skeletal elements and joints are… Expand
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