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SDC1 gene

Known as: CD138 ANTIGEN, SYNDECAN, SDC 
This gene is involved in cell adhesion, signal transduction and cytoskeleton organization.
National Institutes of Health

Related topics

Related topics

7 relations
Cell AdhesionCell-Matrix JunctionCytoskeletal ModelingLigand Binding

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SDC1 wt Allele

Papers overview

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Highly Cited
2007
Highly Cited
2007
Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development
We previously showed that mice with a null mutation in syndecan-1 (Sdc1; CD138) were resistant to Wnt1-induced mammary tumor… 
Highly Cited
2004
Highly Cited
2004
Indian hedgehog and syndecans‐3 coregulate chondrocyte proliferation and function during chick limb skeletogenesis
Hedgehog proteins exert critical roles in embryogenesis and require heparan sulfate proteoglycans (HS‐PGs) for action. Indian… 
Highly Cited
2003
Highly Cited
2003
Syndecan-1-mediated cell spreading requires signaling by alphavbeta3 integrins in human breast carcinoma cells.
Syndecans are cell surface heparan sulfate proteoglycans with regulatory roles in cell adhesion, proliferation, and… 
Highly Cited
2003
Highly Cited
2003
Growth factors regulate the expression profile of their syndecan co-receptors and the differentiation of mesothelioma cells.
BACKGROUND Diffuse malignant pleural mesotheliomas are locally aggressive and highly lethal tumors that are becoming more common… 
Highly Cited
2000
Highly Cited
2000
Syndesmos, a protein that interacts with the cytoplasmic domain of syndecan-4, mediates cell spreading and actin cytoskeletal organization.
Syndecan-4 is a cell surface heparan sulfate proteoglycan which, in cooperation with integrins, transduces signals for the… 
Highly Cited
1995
Highly Cited
1995
Self-association of N-Syndecan (Syndecan-3) Core Protein Is Mediated by a Novel Structural Motif in the Transmembrane Domain and Ectodomain Flanking Region (*)
We expressed domains of the core protein of the transmembrane heparan sulfate proteoglycan N-syndecan (syndecan-3) either… 
1995
1995
Co-expression of heparin-binding growth-associated molecule (HB-GAM) and N-syndecan (syndecan-3) in developing rat brain
Highly Cited
1994
Highly Cited
1994
Aggregation-induced association of syndecan-1 with microfilaments mediated by the cytoplasmic domain.
Expression of the transmembrane proteoglycan syndecan-1 in Schwann cells leads to enhanced spreading and cytoskeletal… 
Highly Cited
1992
Highly Cited
1992
Colocalization of thrombospondin and syndecan during murine development
Thrombospondin is an adhesive glycoprotein that is thought to play a role in tissue genesis and repair. We have used a monoclonal… 
Highly Cited
1989
Highly Cited
1989
Epithelial-mesenchymal interactions regulate the stage-specific expression of a cell surface proteoglycan, syndecan, in the developing kidney.
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