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SCID Mice

Known as: Immunodeficient Mice, Severe Combined, Mice, SCID, SCID Mouse 
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types including cancer stem cells and frequently… Expand
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Review
2018
Review
2018
CD45 is an evolutionary highly conserved receptor protein tyrosine phosphatase exclusively expressed on all nucleated cells of… Expand
Review
2017
Review
2017
Objective To compare loneliness, depressive symptoms and major depressive episodes between empty-nest and not-empty-nest older… Expand
Review
2016
Review
2016
Background Mental disorders are highly prevalent and associated with considerable disease burden and personal and societal costs… Expand
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Highly Cited
2005
Highly Cited
2005
Ethical considerations constrain the in vivo study of human hemopoietic stem cells (HSC). To overcome this limitation, small… Expand
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Highly Cited
2004
Highly Cited
2004
The cancer stem cell (CSC) hypothesis suggests that neoplastic clones are maintained exclusively by a rare fraction of cells with… Expand
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Highly Cited
1997
Highly Cited
1997
On the subject of acute myeloid leukemia (AML), there is little consensus about the target cell within the hematopoietic stem… Expand
Highly Cited
1995
Highly Cited
1995
The scid mutation was backcrossed ten generations onto the NOD/Lt strain background, resulting in an immunodeficient stock (NOD… Expand
Highly Cited
1994
Highly Cited
1994
We have described a murine model of IBD that was induced in C.B-17 scid mice by transfer of the CD45RBhi subpopulation of CD4+ T… Expand
Highly Cited
1988
Highly Cited
1988
The study of human hematopoietic cells and the human immune system is hampered by the lack of a suitable experimental model… Expand