SCID Mice

Known as: Immunodeficient Mice, Severe Combined, Mice, SCID, Mouse, SCID 
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature… (More)

Topic mentions per year

Topic mentions per year

1971-2018
05010015019712018

Papers overview

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Highly Cited
2006
Highly Cited
2006
We tested the hypothesis that multipotent stromal cells from human bone marrow (hMSCs) can provide a potential therapy for human… (More)
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Highly Cited
2005
Highly Cited
2005
Ethical considerations constrain the in vivo study of human hemopoietic stem cells (HSC). To overcome this limitation, small… (More)
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Highly Cited
2002
Highly Cited
2002
To establish a more appropriate animal recipient for xenotransplantation, NOD/SCID/gamma(c)(null) mice double homozygous for the… (More)
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Highly Cited
1997
Highly Cited
1997
Human hematopoiesis originates in a population of stem cells with transplantable lympho-myeloid reconstituting potential, but a… (More)
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Highly Cited
1996
Highly Cited
1996
The development of stem–cell gene therapy is hindered by the absence of repopulation assays for primitive human hematopoietic… (More)
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Highly Cited
1995
Highly Cited
1995
The scid mutation was backcrossed ten generations onto the NOD/Lt strain background, resulting in an immunodeficient stock (NOD… (More)
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Highly Cited
1994
Highly Cited
1994
We have described a murine model of IBD that was induced in C.B-17 scid mice by transfer of the CD45RBhi subpopulation of CD4+ T… (More)
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Highly Cited
1993
Highly Cited
1993
CD4+ T cells in the mouse can be subdivided into two fractions based on the level of expression of the CD45RB determinant… (More)
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Highly Cited
1993
Highly Cited
1993
Precise definition of the role of both CD4 and CD8 T-cell subsets from NOD mice in the adoptive transfer of diabetes has been… (More)
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Highly Cited
1992
Highly Cited
1992
The V(D)J recombination activation gene RAG-1 was isolated on the basis of its ability to activate V(D)J recombination on an… (More)
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