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SCH 66712

Known as: SCH66712 
 
National Institutes of Health

Papers overview

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2018
2018
Metabolic phenotype can be affected by multiple factors, including allelic variation and interactions with inhibitors. Human… Expand
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2015
2015
Cytochrome P450 enzymes (CYPs) are a heme-containing enzyme superfamily that have a major role in the metabolism of drugs in… Expand
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2015
2015
Cytochrome P450s (CYPs) are heme-containing enzymes that metabolize small organic molecules including drugs. CYP3A4 and CYP2D6… Expand
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2014
2014
Cytochrome P450 enzymes (CYPs) represent an important enzyme superfamily involved in metabolism of many endogenous and exogenous… Expand
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2014
2014
Human cytochrome P450 3A4 (CYP3A4) is responsible for the metabolism of more than half of pharmaceutic drugs, and inactivation of… Expand
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2012
2012
Human cytochrome P450 2D6 (CYP2D6) is involved in metabolism of approximately 25% of pharmaceutical drugs. Inactivation of CYP2D6… Expand
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2011
2011
5-Fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine (SCH 66712) is a potent mechanism-based inactivator of… Expand
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2001
2001
SCH 66712 [5-fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine] caused a time- and NADPH-dependent loss of… Expand
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1999
1999
SCH 66712 is a potent and selective dopamine D4 receptor antagonist. An HPLC method was developed for the analysis of SCH 66712… Expand
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