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SCH 66712

Known as: SCH66712 
National Institutes of Health

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2 relations

Broader (2)

ImidazolesPyrimidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
CYP2D6 Allelic Variants *17-2 & 17-3 Metabolize the Same Substrates as *1 but are Less Susceptibility to Inactivation by SCH 66712
2015
2015
Interactions of Human CYP2D6 Polymorphisms with the Mechanism‐Based Inactivator SCH 66712
Cytochrome P450 enzymes (CYPs) are a heme‐containing enzyme superfamily that have a major role in the metabolism of drugs in… 
2015
2015
SCH 66712 and EMTPP are the First Potent Mechanism‐Based Inactivators of Both Human CYP2D6 and CYP3A4
Cytochrome P450s (CYPs) are heme‐containing enzymes that metabolize small organic molecules including drugs. CYP3A4 and CYP2D6… 
2011
2011
Use of AutoDock Modeling to Understand Inactivation of Human Cytochrome P450 2D6 by SCH 66712
AutoDock is a free‐ware program that simulates ligand‐binding to the active site of a protein based on three‐dimensional… 
1999
1999
High-performance liquid chromatographic analysis of the D4 receptor antagonist SCH 66712 in rat plasma.
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