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SCH 66712

Known as: SCH66712 
National Institutes of Health

Papers overview

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2018
2018
Metabolic phenotype can be affected by multiple factors, including allelic variation and interactions with inhibitors. Human… 
2015
2015
Cytochrome P450 enzymes (CYPs) are a heme‐containing enzyme superfamily that have a major role in the metabolism of drugs in… 
2015
2015
Cytochrome P450s (CYPs) are heme‐containing enzymes that metabolize small organic molecules including drugs. CYP3A4 and CYP2D6… 
2014
2014
Cytochrome P450 enzymes (CYPs) represent an important enzyme superfamily involved in metabolism of many endogenous and exogenous… 
2014
2014
Human cytochrome P450 3A4 (CYP3A4) is responsible for the metabolism of more than half of pharmaceutic drugs, and inactivation of… 
2012
2012
Human cytochrome P450 2D6 (CYP2D6) is involved in metabolism of approximately 25% of pharmaceutical drugs. Inactivation of CYP2D6… 
2011
2011
5-Fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine (SCH 66712) is a potent mechanism-based inactivator of… 
2011
2011
AutoDock is a free‐ware program that simulates ligand‐binding to the active site of a protein based on three‐dimensional… 
2001
2001
SCH 66712 [5-fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine] caused a time- and NADPH-dependent loss of…