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SCH-58500

Known as: ACN53, Recombinant Adenovirus-p53 SCH-58500, SCH 58500 
A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity… 
National Institutes of Health

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Broader (1)

Recombinant Adenovirus-p53

Papers overview

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2002
2002
Porcine Toxicology Studies of SCH 58500, an Adenoviral Vector for the p53 Gene
Abstract Adenoviral vectors are being actively investigated for their potential utility in gene therapy. SCH 58500, a replication… 
2002
2002
Intravesical instillation of SCH 58500 transfers p53 in bladder cancer
  • 2002
  • Corpus ID: 195147036
2000
2000
NK cells mediate the anti-tumor effects of E1-deleted, type 5 adenovirus in a human tumor xenograft model.
SCH58500 (ACN53) is a recombinant adenovirus expressing human p53 for gene therapy of cancer. In preclinical studies, SCH58500… 
2000
2000
Combination therapy with SCH58500 (p53 adenovirus) and cyclophosphamide in preclinical cancer models.
SCH58500 (ACN53) is a replication-deficient, recombinant adenovirus which expresses human p53 tumor suppressor. In preclinical… 
Review
2000
Review
2000
Technology evaluation: Sch-58500, Canji.
  • Dale L. Barnard
  • Current opinion in molecular therapeutics (Print)
  • 2000
  • Corpus ID: 10566107
Sch-58500 is a gene therapy utilizing the p53 gene and is under development by Canji and Schering-Plough for the potential… 
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