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SCH-503034

Known as: Sch 503034, Sch503034 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

boceprevir

Papers overview

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Highly Cited
2010
Highly Cited
2010
The hepatitis C virus (HCV) NS4B RNA binding inhibitor clemizole is highly synergistic with HCV protease inhibitors.
BACKGROUND We recently identified a compound, clemizole hydrochloride, that inhibits NS4B's RNA binding and hepatitis C virus… 
Highly Cited
2010
Highly Cited
2010
Susceptibility of Treatment-Naive Hepatitis C Virus (HCV) Clinical Isolates to HCV Protease Inhibitors
ABSTRACT In order to assess the natural variation in susceptibility to hepatitis C virus (HCV) NS3 protease inhibitors (PIs… 
Review
2010
Review
2010
Boceprevir
Boceprevir (SCH 503034; SCH-503034) is a peptidomimetic NS3/4A serine protease inhibitor, representing a new class of hepatitis C… 
2009
2009
HCV-NS3 inhibitors: determination of their kinetic parameters and mechanism.
2009
2009
Toward the back-up of boceprevir (SCH 503034): discovery of new extended P4-capped ketoamide inhibitors of hepatitis C virus NS3 serine protease with improved potency and pharmacokinetic profiles.
Hepatitis C is the most prevalent liver disease. Viral hepatitis C (HCV), a small (+)-RNA virus, infects chronically an estimated… 
Highly Cited
2008
Highly Cited
2008
Characterization of resistance mutations against HCV ketoamide protease inhibitors.
2008
2008
65 CLONAL ANALYSIS OF MUTATIONS SELECTED IN THE HCV NS3 PROTEASE DOMAIN OF GENOTYPE 1 NON-RESPONDERS TREATED WITH BOCEPREVIR (SCH503034)
Review
2008
Review
2008
Advances in genomic research on hepatitis C virus with a useful tool, replicon system.
The research for hepatitis C virus (HCV) has long delayed by missing of in vitro culture system. Since the development of… 
2007
2007
Pharmacokinetic Enhancement of the Hepatitis C Virus Protease Inhibitors VX-950 and SCH 503034 by Co-Dosing with Ritonavir
Inhibitors of hepatitis C virus (HCV) protease have shown marked antiviral activity in short-term clinical studies in HCV… 
Highly Cited
2006
Highly Cited
2006
Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S…
Hepatitis C virus (HCV) infection is the major cause of chronic liver disease, leading to cirrhosis and hepatocellular carcinoma… 
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