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SCH-503034

Known as: Sch 503034, Sch503034 
National Institutes of Health

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1 relation

Broader (1)

boceprevir

Papers overview

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2015
2015
Generation of a Chimeric Hepatitis C Replicon Encoding a Genotype-6a NS3 Protease and Assessment of Boceprevir (SCH503034) Sensitivity and Drug-Associated Mutations
Background Genotype (gt)6 HCV is common amongst HCV-positive populations of the Asia–Pacific region but cell culture models for… 
2013
2013
Replication of the subgenomic hepatitis C virus replicon in the presence of the NS3 protease inhibitors: a stochastic model
The hepatitis C virus (HCV) belongs to Flaviviridae family and causes hazardous liver diseases leading frequently to cirrhosis… 
2013
2013
Replication of the subgenomic hepatitis C virus replicon in the presence of the NS3 protease inhibitors: a stochastic model
The hepatitis C virus (HCV) belongs to Flaviviridae family and causes hazardous liver diseases leading frequently to cirrhosis… 
2009
2009
Discovery of novel P3 sulfonamide-capped inhibitors of HCV NS3 protease. Inhibitors with improved cellular potencies.
2008
2008
65 CLONAL ANALYSIS OF MUTATIONS SELECTED IN THE HCV NS3 PROTEASE DOMAIN OF GENOTYPE 1 NON-RESPONDERS TREATED WITH BOCEPREVIR (SCH503034)
Review
2008
Review
2008
Advances in genomic research on hepatitis C virus with a useful tool, replicon system.
The research for hepatitis C virus (HCV) has long delayed by missing of in vitro culture system. Since the development of… 
2008
2008
Klonale Analyse von Mutationen der HCV NS3 Protease bei Genotyp 1 Non-Respondern, die mit Boceprevir (SCH503034) behandelt wurden
Einleitung: Das Hepatitis C Virus liegt wegen der relativ ungenau arbeitenden HCV RNA Polymerase, als Population von Quasispezies… 
Highly Cited
2008
Highly Cited
2008
Selection and Characterization of Hepatitis C Virus Replicons Dually Resistant to the Polymerase and Protease Inhibitors HCV-796 and Boceprevir (SCH 503034)
ABSTRACT HCV-796 is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase, and… 
2007
2007
[545] SCH 503034, AN ORAL HCV PROTEASE INHIBITOR, IS WELL-TOLERATED IN PATIENTS WITH VARYING DEGREES OF HEPATIC IMPAIRMENT
2005
2005
Interferon in Replicon Cells Enhances the Antiviral Activity of Alpha Suppresses Polyprotein Maturation and of Hepatitis C Virus NS 3 Protease , SCH 503034 , a Mechanism-Based Inhibitor
10.1128/AAC.50.3.1013-1020.2006. 2006, 50(3):1013. DOI: Antimicrob. Agents Chemother. Girijavallabhan and F. G. Njoroge A… 
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