SCH-503034

Known as: Sch 503034, Sch503034 
 

Topic mentions per year

Topic mentions per year

2005-2013
051020052013

Papers overview

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2010
2010
Small-molecule hepatitis C virus (HCV) NS3 protease inhibitors such as boceprevir (SCH 503034) have been shown to have antiviral… (More)
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2009
2009
HCV-796 is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase, and boceprevir is… (More)
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2009
2009
The purpose of this study was to develop a specific and highly sensitive method based on fast sample preparation and LC-MS/MS… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS SCH 503034 is a novel and potent oral hepatitis C virus (HCV) protease inhibitor. In this phase Ib study, we… (More)
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2007
2007
Inhibitors of hepatitis C virus (HCV) protease have shown marked antiviral activity in short-term clinical studies in HCV… (More)
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2007
2007
The structures of both the native holo-HCV NS3/4A protease domain and the protease domain with a serine 139 to alanine (S139A… (More)
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2007
2007
This paper describes the development and qualification of a fast, sensitive and specific ultra-performance liquid chromatography… (More)
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Highly Cited
2006
Highly Cited
2006
HCV NS3 protease variants resistant to the protease inhibitor SCH 503034 were selected. Three mutations, T54A, V170A and A156S… (More)
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Highly Cited
2006
Highly Cited
2006
Cleavage of the hepatitis C virus (HCV) polyprotein by the viral NS3 protease releases functional viral proteins essential for… (More)
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2006
2006
Hepatitis C virus (HCV) infection is the major cause of chronic liver disease, leading to cirrhosis and hepatocellular carcinoma… (More)
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