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SCH 42495

Known as: SCH-42495 
 
National Institutes of Health

Papers overview

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2002
2002
Objective The effects of combined inhibition of neutral endopeptidase (NEP) with either angiotensin-converting enzyme (ACE), or… Expand
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1999
1999
Brain natriuretic peptide (BNP) is increased in left ventricular impairment and neutral endopeptidase (NEP) is involved in its… Expand
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Highly Cited
1998
Highly Cited
1998
It has been suggested that combined inhibition of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) may lower… Expand
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1997
1997
1. Inhibition of neutral endopeptidase (NEP), the degradative enzyme for atrial natriuretic peptide, was studied in vitro and in… Expand
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1994
1994
The antihypertensive effects and safety of a novel neutral endopeptidase inhibitor, SCH 42495, were investigated in hypertensive… Expand
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1994
1994
1. We have investigated the effects of inhibition of neutral endopeptidase on the cardiovascular remodelling secondary to chronic… Expand
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1994
1994
Summary: Blockade of atrial natriuretic factor (ANF) degradation by specific neutral endopeptidase (NEP) inhibitors may be useful… Expand
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Highly Cited
1993
Highly Cited
1993
The detailed integrated renal, hormonal, and hemodynamic effects of acute (first dose) and established (4 days) inhibition of… Expand
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1993
1993
Neutral metalloendopeptidase (NEP) inhibitors delay atrial natriuretic factor (ANF) catabolism and potentiate biological… Expand
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1993
1993
In contrast to the wealth of information available concerning the response of plasma atrial natriuretic peptide to changes in… Expand
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