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SC 791

Known as: SC-791, SC791 cpd 
 
National Institutes of Health

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2 relations

Broader (2)

IsoxazolesSulfonamides

Papers overview

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2012
2012
Inhibition of Ion Channels and Heart Beat in Drosophila by Selective COX-2 Inhibitor SC-791
Recent findings suggest that modulation of ion channels might be implicated in some of the clinical effects of coxibs, selective… Expand
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2012
2012
Ultraviolet C Irradiation Induces Different Expression of Cyclooxygenase 2 in NIH 3T3 Cells and A431 Cells: The Roles of COX-2 Are Different in Various Cell Lines
Ultraviolet C (UVC) is a DNA damage inducer, and 20 J/m(2) of UVC irradiation caused cell growth inhibition and induced cell… Expand
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2010
2010
Mechanism of Kv2.1 channel inhibition by a selective COX-2 inhibitor SC-791—modification of gating
Recent research suggests that some clinical effects of coxibs, selective inhibitors of cyclooxygenase-2 (COX-2), can be mediated… Expand
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2005
2005
Screening New Drugs for Immunotoxic Potential: II. Assessment of the Effects of Selective and Nonselective COX-2 Inhibitors on Complement Activation, Superoxide Anion Production and Leukocyte…
Results from earlier experiments in our laboratories revealed that both selective and nonselective inhibitors of cyclooxygenase-2… Expand
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2005
2005
Screening New Drugs for Immunotoxic Potential: I. Assessment of the Effects of Conventional Nonsteroidal Anti-Inflammatory Drugs and Selective COX-2 Inhibitors on In Vitro and In Vivo Phagocytic…
Abstract Although both experimental and clinical literature contain reports suggestive of associations between enhanced… Expand
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2005
2005
Screening New Drugs for Immunotoxic Potential: III. Assessment of the Effects of Selective and Nonselective COX-2 Inhibitors on T-Cell-Dependent Antibody and Natural Killer Cell Responses in the Rat
Results from earlier experiments in our laboratories revealed that both selective and non-selective inhibitors of cyclooxygenase… Expand
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2003
2003
Selective cyclooxygenase-2 inhibition does not affect the healing of cutaneous full-thickness incisional wounds in SKH-1 mice.
BACKGROUND The inducible cyclooxygenase-2 (COX-2) enzyme is upregulated in inflammatory diseases, as well as in epithelial… Expand
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Highly Cited
2003
Highly Cited
2003
Epidermal COX-2 induction following ultraviolet irradiation: suggested mechanism for the role of COX-2 inhibition in photoprotection.
The cyclooxygenase isoforms, COX-1 and COX-2, are involved in the biosynthesis of prostaglandin E2, a major prostaglandin… Expand
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