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SB-435495

National Institutes of Health

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2 relations

Broader (2)

Biphenyl CompoundsPyrimidinones

Papers overview

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2003
2003
The Discovery of SB-435495: A Potent, Orally Active Inhibitor of Lipoprotein-Associated Phospholipase A2 for Evaluation in Man.
A significant problem in cancer treatment is the development of tumor resistance to chemotherapeutic agents. Acquired drug… 
2001
2001
Lp-PLA2 inhibitors (GlaxoSmithKline).
  • M. Booker
  • IDrugs : the investigational drugs journal
  • 2001
  • Corpus ID: 40339235
GlaxoSmithKline is investigating a series of substituted pyrimidin-4-ones, including SB-435495, as reversible inhibitors of… 
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