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SB 216763

Known as: 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, SB-216763, SB216763 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The transcription factor NF-E2-related factor 2 (Nrf2) is a master regulator of a genetic program, termed the phase 2 response… Expand
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Highly Cited
2009
Highly Cited
2009
Arachidonic acid (AA, a proinflammatory fatty acid) in combination with iron promotes excess reactive oxygen species (ROS… Expand
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Highly Cited
2009
Highly Cited
2009
Cancers are driven by a population of cells with the stem cell properties of self-renewal and unlimited growth. As a… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Opening of the mitochondrial permeability transition pore (mPTP) is a crucial event in lethal reperfusion injury… Expand
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Highly Cited
2008
Highly Cited
2008
Repetitive cycles of reflow/reocclusion in the initial 2 min following release of a prolonged coronary occlusion, i.e., ischemic… Expand
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Highly Cited
2008
Highly Cited
2008
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder in the Western world. PTEN (phosphatase/tensin… Expand
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Highly Cited
2007
Highly Cited
2007
Activation of glycogen synthase kinase-3 (GSK-3) can cause memory deficits as seen in Alzheimer's disease, the most common age… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Serine-threonine protein kinase glycogen synthase kinase (GSK)-3 is involved in regulation of many cell functions, but… Expand
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Highly Cited
2002
Highly Cited
2002
Hypoxia triggers apoptosis in a number of different cell types largely through a mitochondrial cell death pathway, which can be… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase, the activity of which is inhibited by a… Expand
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