Skip to search formSkip to main contentSkip to account menu

SB 216763

Known as: 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, SB-216763, SB216763 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

IndolesMaleimides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
GSK3 inhibition reduces inflammatory responses of microglia and upregulates Il-10 production
Introduction: Neurodegeneration resulting from pathogen invasion or tissue damage has been associated with activation of… 
2017
2017
[Protective effect of glycogen synthase kinase 3β inhibition via peroxisome proliferator-activated receptor alpha activation in mice with acute liver failure].
Objective: To investigate the role of the glycogen synthase kinase 3β (GSK3β) and the peroxisome proliferator-activated receptor… 
2016
2016
Hydrosulfide attenuates acute myocardial ischemic injury through the glycogen synthase kinase-3β/β-catenin signaling pathway
The endogenous signaling gasotransmitter, hydrosulfide (H2S), has been shown to exert cardioprotective effects against acute… 
2015
2015
Dickkopf ‐ 3 ( Dkk 3 ) induces apoptosis in cisplatin ‐ resistant lung adenocarcinoma cells via the Wnt / β ‐ catenin pathway
Previous studies have shown that Dickkopf‐3 (Dkk3) is inactivated in lung cancer cells, while the inactivation of the Wnt… 
2013
2013
Inhibition of Wnt / b-catenin signaling mediates ursolic acid-induced apoptosis in PC-3 prostate cancer cells
Background: Ursolic acid, a pentacyclic triterpenoid, is known to exert antitumor activity in breast, lung, liver and colon… 
2013
2013
PI3K signaling mediates diverse regulation of ATF4 expression for the survival of HK-2 cells exposed to cadmium
Cadmium exposure causes endoplasmic reticulum (ER) stress and accumulation of activating transcription factor 4 (ATF4), an ER… 
2012
2012
Signaling and Regulation GSK-3 Promotes Cell Survival , Growth , and PAX 3 Levels in Human Melanoma Cells
GSK-3 is a serine/threonine kinase involved in a diverse range of cellular processes. GSK-3 exists in two isoforms, GSK-3a and… 
2009
2009
Regulation of Serotonin 1 B Receptor by Glycogen Synthase Kinase-3
In response to 5-hydroxytryptamine (5-HT), the type 1 serotonin receptors (5-HT1Rs) preferentially couple to the inhibitory G… 
Review
2009
Review
2009
The Glycogen Synthase Kinase Inhibitor 3-( 2 , 4-Dichlorophenyl )-4-( 1-methyl-1 H-indol-3-yl )-1 H-pyrrole-2 , 5-dione ( SB 216763 ) Is a Partial Agonist of the Aryl Hydrocarbon Receptor
  • 2009
  • Corpus ID: 37672785
Kinase inhibitors are frequently used tools in signal transduction research. 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl… 
2009
2009
IDENTIFICATION OFAIPASAGSK-3 BINDING PROTEIN
GSK-3, a well-known serine/threonine kinase is one of the key players controlling numerous cellular and physiological processes… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)