Maleimides

Known as: Maleimides [Chemical/Ingredient], maleimide 
Derivatives of maleimide (the structural formula H2C2(CO)2NH) containing a pyrroledione ring where the hydrogen atom of the NH group is replaced with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Many antibody-drug conjugates (ADCs) are unstable in vivo because they are formed from maleimide-containing components conjugated… (More)
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Highly Cited
2012
Highly Cited
2012
Hydrogels, highly hydrated cross-linked polymer networks, have emerged as powerful synthetic analogues of extracellular matrices… (More)
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Highly Cited
2012
Highly Cited
2012
The reactive thiol in cysteine is used for coupling maleimide linkers in the generation of antibody conjugates. To assess the… (More)
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Highly Cited
2011
Highly Cited
2011
Addition chemistries are widely used in preparing biological conjugates, and in particular, maleimide-thiol adducts have been… (More)
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Highly Cited
2009
Highly Cited
2009
Adv. Mater. 2009, 21, 431–434 2009 WILEY-VCH Verlag Gm T IO N Immobilization of biomolecules onto surfaces is important in many… (More)
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Highly Cited
2004
Highly Cited
2004
A single molecule fluorescence assay is presented for studying the mechanism of soluble N-ethyl maleimide sensitive-factor… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase, the activity of which is inhibited by a… (More)
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Highly Cited
1999
Highly Cited
1999
The newly introduced sulfhydryl reductant tris(2-carboxyethyl)phosphine (TCEP) is a potentially attractive alternative to… (More)
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Highly Cited
1997
Highly Cited
1997
Stimulation of the mitochondrial permeability transition (MPT) in de-energized mitochondria by phenylarsine oxide (PheArs) is… (More)
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Highly Cited
1996
Highly Cited
1996
Immunoliposomes (antibody-directed liposomes) were used in the present study for delivery of the antineoplastic agent daunomycin… (More)
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