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SAIT301

Known as: Anti-C-met Monoclonal Antibody SAIT301 
A humanized monoclonal antibody targeting the alpha chain of the extracellular domain of human hepatocyte growth factor receptor (HGFR or c-Met… 
National Institutes of Health

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2 relations

Broader (1)

Monoclonal Antibodies
antigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Abstract 662: USP8 modulates ubiquitination of LRIG1 for Met degradation
The Met receptor tyrosine kinase is an attractive target for cancer therapy as it promotes invasive tumor growth. SAIT301 is a… 
2015
2015
Abstract 661: Increasing sensitivity of SAIT301, a specific monoclonal antibody of c-Met, with paclitaxel combination in c-Met positive gastric cancer
The c-Met is frequently overexpressed and related to a worse prognosis in gastric carcinoma (GC). This study aimed to determine a… 
2014
2014
Abstract LB-219: Synthetic lethal screening reveals FGFR as one of combinatorial targets to overcome resistance to Met-targeted therapy
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Met is a receptor tyrosine kinase that promotes cancer… 
2013
2013
Abstract 1036: Cbl-independent degradation of Met: Ways to avoid agonism of bivalent Met targeting antibody.
The Met receptor tyrosine kinase, found to be constitutively activated in many tumors, has become a leading target for cancer… 
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