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SAICAR

Known as: 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole, 5-amino-4-imidazole-N-succinocarboxamide ribonucleotide, succinyl-AICAR 
 
National Institutes of Health

Papers overview

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2018
2018
Expanding the scope and applications of anionic N-heterocyclic carbenes (NHCs), a novel series of magnesium NHC complexes is… Expand
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2014
2014
2-butyl-5-chloro-4-formyl-3H-imidazole 1 was condensed with the potentially bioactive 5- chloromethyl-6-methyl-benzo [1,3… Expand
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2013
2013
The enzyme SAICAR synthetase ligates aspartate with CAIR (5'-phosphoribosyl-4-carboxy-5-aminoimidazole) forming SAICAR (5-amino-4… Expand
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Highly Cited
2012
Highly Cited
2012
Pyruvate kinase isoform M2 (PKM2) plays an important role in the growth and metabolic reprogramming of cancer cells in stress… Expand
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2009
2009
Adenylosuccinate lyase (ASL) catalyzes two distinct but chemically similar reactions in purine biosynthesis. The first, exclusive… Expand
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2006
2006
As a part of a structural genomics program, the 2.2 angstroms resolution crystal structure of the PurC gene product from… Expand
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2005
2005
SummaryThe enzyme adenylosuccinate lyase (ADSL) intervenes twice in the biosynthesis of adenine nucleotides. ADSL deficiency is… Expand
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1998
1998
BACKGROUND The biosynthesis of key metabolic components is of major interest to biologists. Studies of de novo purine synthesis… Expand
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1996
1996
All previously reported CAAX-based farnesyltransferase inhibitors contain a thiol functionality. We report that attachment of the… Expand
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1979
1979
Abstract The metabolism of alanosine. dl -2-amino-3-( N -hydroxy, N -nitrosamino) propionic acid (NSC-143647), a new antitumor… Expand
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