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SAICAR

Known as: 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole, 5-amino-4-imidazole-N-succinocarboxamide ribonucleotide, succinyl-AICAR 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Aminoimidazole CarboxamideRibonucleotides
Phosphoribosylaminoimidazole-succinocarboxamide synthaseanalogs & derivatives

Narrower (1)

SAICAR, (D)-isomer

Papers overview

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2014
2014
SAICAR binding activates PKM2 protein kinase activity.
SAICAR-mediated PKM2 protein kinase activity is necessary for EGF-induced cancer cell proliferation. 
2014
2014
Synthesis and characterization of novel 3-substituted-2-butyl-5-chloro-imidazol- 4-carbaldehyde derivatives
2-butyl-5-chloro-4-formyl-3H-imidazole 1 was condensed with the potentially bioactive 5- chloromethyl-6-methyl-benzo [1,3… 
2014
2014
Keller Cancer Cell Survival in Glucose-Limited Conditions SAICAR Stimulates Pyruvate Kinase Isoform M 2 and Promotes
, 1069 (2012); 338 Science et al. Kirstie E. Keller Cancer Cell Survival in Glucose-Limited Conditions SAICAR Stimulates… 
2012
2012
Neue Imidazol- und Indolderivate -Synthese und biologische in-vitro-Prüfungen
Diese Arbeit bestehend aus 2 Teilen. Im ersten Teil sollte eine Reihe von neuen N (3-(4-(Pyridin-3yl)-1H-imidazol-2-ylamino… 
2012
2012
Mad1 doubles as nuclear import regulator
Glucose metabolism is often altered in cancer to promote cell survival under stress. SAICAR (succinylaminoimidazolecarboxamide… 
2012
2012
Multiple Mechanisms Mediating the Starvation Induced Activation of Recombination at HIS4 in Saccharomyces Cerevisiae
Meiotic recombination occurs at relatively high levels at specific regions in the genome called hotspots. The transcription… 
2010
2010
Synthesis, spectral and microbial studies of 3-{4-[2-methyl-4-(4-methoxybenzylidene)-5-oxo-imidazol- 1-yl]phenyl}-2-(substituted phenyl)-1,3-thiazolidin- 4-one
3-{4-[2-methyl-4-(4-methoxybenzylidene)-5-oxo-imidazol- 1-yl]phenyl}-2- (substituted phenyl)-1,3-thiazolidin- 4-one have been… 
1992
1992
Förfarande för framställning av ett terapeutiskt användbart imidazol-, triazol- eller tetrazolderivat
1992
1992
[Substrate specificity of phosphoribosyl-aminoimidazole-succinocarboxamide synthetase (SAICAR-synthetase) from Saccharomyces cerevisiae yeast].
The substrate specificity of phosphoribosyl-aminoimidazole-succinocarboxamide-synthetase (SAICAR-synthetase, EC 6.3.2.6) of the… 
1992
1992
Imidazol-, triatzol- Science tetrazolderivat.