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SAICAR

Known as: 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole, 5-amino-4-imidazole-N-succinocarboxamide ribonucleotide, succinyl-AICAR 
National Institutes of Health

Papers overview

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2018
2018
Expanding the scope and applications of anionic N-heterocyclic carbenes (NHCs), a novel series of magnesium NHC complexes is… 
2013
2013
The enzyme SAICAR synthetase ligates aspartate with CAIR (5'-phosphoribosyl-4-carboxy-5-aminoimidazole) forming SAICAR (5-amino-4… 
Highly Cited
2012
Highly Cited
2012
A metabolite is identified that may help cancer cells coordinate their mode of energy generation with nutrient conditions… 
2006
2006
The crystal structure of phophoribosylaminoimidazole-succinocarboxamide or SAICAR synthase from T. maritima at 2.2 Å revealed an… 
2005
2005
SummaryThe enzyme adenylosuccinate lyase (ADSL) intervenes twice in the biosynthesis of adenine nucleotides. ADSL deficiency is… 
Highly Cited
1996
Highly Cited
1996
All previously reported CAAX-based farnesyltransferase inhibitors contain a thiol functionality. We report that attachment of the… 
1979
1979
1973
1973
  • L. Brox
  • Canadian journal of biochemistry
  • 1973
  • Corpus ID: 46197545
Adenylosuccinate lyase (EC 4.3.2.2), which catalyzes the conversion of either adenylosuccinate (AMPS) or 5-amino-4-imidazole-N…