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SAICAR

Known as: 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole, 5-amino-4-imidazole-N-succinocarboxamide ribonucleotide, succinyl-AICAR 
 
National Institutes of Health

Papers overview

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2018
2018
Expanding the scope and applications of anionic N-heterocyclic carbenes (NHCs), a novel series of magnesium NHC complexes is… Expand
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2013
2013
The enzyme SAICAR synthetase ligates aspartate with CAIR (5'-phosphoribosyl-4-carboxy-5-aminoimidazole) forming SAICAR (5-amino-4… Expand
Highly Cited
2012
Highly Cited
2012
A metabolite is identified that may help cancer cells coordinate their mode of energy generation with nutrient conditions… Expand
2009
2009
Adenylosuccinate lyase (ASL) catalyzes two distinct but chemically similar reactions in purine biosynthesis. The first, exclusive… Expand
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2006
2006
The crystal structure of phophoribosylaminoimidazole-succinocarboxamide or SAICAR synthase from T. maritima at 2.2 Å revealed an… Expand
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1998
1998
BACKGROUND The biosynthesis of key metabolic components is of major interest to biologists. Studies of de novo purine synthesis… Expand
Highly Cited
1996
Highly Cited
1996
All previously reported CAAX-based farnesyltransferase inhibitors contain a thiol functionality. We report that attachment of the… Expand
1980
1980
Two complementary methods have been devised for measuring the activity of 5-amino-4-imidazole-N-succinocarboxamide ribonucleotide… Expand
1979
1979
Abstract The metabolism of alanosine. dl -2-amino-3-( N -hydroxy, N -nitrosamino) propionic acid (NSC-143647), a new antitumor… Expand
1973
1973
  • L. Brox
  • Canadian journal of biochemistry
  • 1973
  • Corpus ID: 46197545
Adenylosuccinate lyase (EC 4.3.2.2), which catalyzes the conversion of either adenylosuccinate (AMPS) or 5-amino-4-imidazole-N… Expand