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Aminoimidazole Carboxamide

Known as: 1H-Imidazole-4-carboxamide, 5-amino-, Aminoimidazole Carboxamide [Chemical/Ingredient], Carboxamide, Aminoimidazole 
An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a… Expand
National Institutes of Health

Papers overview

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2015
2015
Ghrelin is involved in the regulation of somatic growth, feeding behavior and energy homeostasis. Ghrelin stimulates neuropeptide… Expand
2013
2013
Tbc1d1 is involved in AICAR-dependent GLUT4 liberation. Tbc1d1 acquires temporal insulin responsiveness with AICAR pretreatment… Expand
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2013
2013
BackgroundHigh fat feeding increases hepatic fat accumulation and is associated with hepatic insulin resistance. AMP Activated… Expand
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Highly Cited
2012
Highly Cited
2012
Elevated circulating saturated fatty acids concentration is commonly associated with poorly controlled diabetes. The highly… Expand
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Highly Cited
2011
Highly Cited
2011
Aims/hypothesisMuscle may experience hypoglycaemia during ischaemia or insulin infusion. During severe hypoglycaemia energy… Expand
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2006
2006
The enzyme fructose-1,6-bisphosphatase (FBP) is key regulatory point in gluconeogenesis. Mutants of Salmonella enterica lacking… Expand
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Highly Cited
1999
Highly Cited
1999
Dacarbazine (DTIC), a widely used anticancer agent, is inactive until metabolized in the liver by cytochromes P450 to form the… Expand
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1998
1998
OBJECTIVE To study the efficacy, toxicity, and antifolate activities of 7-hydroxymethotrexate (7-OH-MTX) versus methotrexate (MTX… Expand
1989
1989
Methenyltetrahydrofolate synthetase (EC 6.3.3.2) catalyzes the irreversible ATP and Mg2+-dependent transformation of 5… Expand
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Highly Cited
1988
Highly Cited
1988
A nitroreductase enzyme has been isolated from Walker 256 rat carcinoma cells which can convert 5-(aziridin-1-yl)-2,4… Expand