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AICA ribonucleotide

Known as: AICA-Ribotide, 5-Amino-4-Imidazolecarboxamide Ribonucleoside 5'-Monophosphate, 5'-Phosphoribosyl-5-Amino-4-Imidazolecarboxamide 
A ribonucleotide analog of adenosine monophosphate that is an intermediate in the synthesis of inosine monophosphate with potential cardioprotective… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Aminoimidazole CarboxamideHypoglycemic AgentsRibonucleotides
analogs & derivatives

Papers overview

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1984
1984
An antibody probe to determine the native species of glycinamide ribonucleotide transformylase in chicken liver.
Antibody probes of Western blots [Renart, J., Reiser, J., & Stark, G. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 3116] of chicken… 
Highly Cited
1981
Highly Cited
1981
On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver.
Tests of 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) and glycinamide ribonucleotide (GAR) transformylase cofactor… 
1981
1981
Escherichia coli deoxyribonucleic acid dependent ribonucleic acid polymerase transcriptional pause sites on SV40 DNA F1.
We have studied elongation of SV40 DNA F1 by E. coli RNA polymerase looking specifically at the length of the transcript as a… 
Highly Cited
1979
Highly Cited
1979
Folylpoly-gamma-glutamates as cosubstrates of 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase.
N10-Formyltetrahydropteroylpoly-gamma-glutamates (N10-formyl-H4PteGlun) having n = 1, 3, 4, 5, 6, and 7 glutamyl residues have… 
1978
1978
N10-Formyltetrahydrofolate is the formyl donor for glycinamide ribotide transformylase in Escherichia coli.
Glycinamide ribotide transformylase from Escherichia coli was obtained free of N5,N10-methenyltetrahydrofolate cyclohydrolase… 
1977
1977
Initiation of RNA synthesis in isolated nuclei.
Ribonucleotide triphosphates, labeled at the beta position, were synthesized and used directly to quantify RNA chain initiation… 
1968
1968
Nucleoside antibiotics. I. Biochemical tools for studying the structural requirements for interaction at the catalytic and regulatory sites of ribonucleotide reductase from Lactobacillus leichmannii.
Abstract The structural requirements for reactivity at the substrate site and for interaction at the regulatory site of… 
1968
1968
Biosynthesis of the purines. XXX. Isolation and characterization of formylglycinamide ribonucleotide amidotransferase-glutamyl complex.
Abstract An enzyme-substrate (glutamine) complex was isolated from an incubation of highly purified formylglycinamide… 
Highly Cited
1960
Highly Cited
1960
A mechanism of resistance to 6-mercaptopurine: metabolism of hypoxanthine and 6-mercaptopurine by sensitive and resistant neoplasms.
Summary Leukemia L1210 ascites tumor cells sensitive to inhibition by 6-mercaptopurine were observed to metabolize hypoxanthine-8… 
Highly Cited
1951
Highly Cited
1951
The biosynthesis of the purines.
GAR transformylase, which is responsible for the incorporation of formate carbon into what becomes position 8 of the purine ring…