FAQ

SAE1 wt Allele

Known as: AOS1, SUA1, HSPC140 
Human SAE1 wild-type allele is located in the vicinity of 19q13.32 and is approximately 80 kb in length. This allele, which encodes SUMO-activating… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2017
01220112017

Related topics

Related topics

6 relations
19q13.32Endoplasmic Reticulum Degradation PathwayPost-Translational Protein ProcessingSumoylation Pathway
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Broader (1)

SAE1 gene

Related mentions per year

Related mentions per year

1947-2018
19401960198020002020
SAE1 wt Allele
Post-Translational Protein Processing
Ubiquitin-mediated Proteolysis Pathway
SAE1 gene
19q13.32
Sumoylation Pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS.
Downregulation in the astroglial glutamate transporter EAAT2 in amyotrophic lateral sclerosis (ALS) patients and mutant SOD1… (More)
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2014
2014
Versatile Recombinant SUMOylation System for the Production of SUMO-Modified Protein
Posttranslational modification by small ubiquitin-like modifiers (SUMO) is being associated with a growing number of regulatory… (More)
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2013
2013
Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT₁A receptor: characterization and subcellular distribution of sumoylated 5-HT₁A receptors.
Sumoylation is a recently described post-translational modification and only a few sumoylated neurotransmitter receptors are… (More)
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2011
2011
Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2.
Dysregulation of glutamate handling ensuing downregulation of expression and activity levels of the astroglial glutamate… (More)
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2011
2011
Therapeutics , Targets , and Chemical Biology Effect of ON 01910 . Na , an Anticancer Mitotic Inhibitor , on Cell-Cycle Progression Correlates with RanGAP 1 Hyperphosphorylation
The benzyl styryl sulfone, ON 01910.Na, is a novel anticancer agent that inhibits mitotic progression and induces apoptosis in… (More)
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