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SAE1 wt Allele

Known as: AOS1, SUA1, HSPC140 
Human SAE1 wild-type allele is located in the vicinity of 19q13.32 and is approximately 80 kb in length. This allele, which encodes SUMO-activating… Expand
National Institutes of Health

Related topics

Related topics

6 relations
19q13.32Endoplasmic Reticulum Degradation PathwayPost-Translational Protein ProcessingSumoylation Pathway
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Broader (1)

SAE1 gene

Papers overview

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2017
2017
Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS
ABSTRACT Downregulation in the astroglial glutamate transporter EAAT2 in amyotrophic lateral sclerosis (ALS) patients and mutant… Expand
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2015
2015
The biochemistry of DNA Oxidation- and repair-mediated active DNA demethylation
Posttranslational modification by small ubiquitin-like modifiers (SUMO) is being associated with a growing number of regulatory… Expand
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2014
2014
Versatile Recombinant SUMOylation System for the Production of SUMO-Modified Protein
Posttranslational modification by small ubiquitin-like modifiers (SUMO) is being associated with a growing number of regulatory… Expand
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2013
2013
Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT1A receptor: Characterization and subcellular distribution of sumoylated 5-HT1A receptors
Sumoylation is a recently described post-translational modification and only a few sumoylated neurotransmitter receptors are… Expand
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2011
2011
Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2.
Dysregulation of glutamate handling ensuing downregulation of expression and activity levels of the astroglial glutamate… Expand
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2011
2011
Effect of ON 01910.Na, an anticancer mitotic inhibitor, on cell-cycle progression correlates with RanGAP1 hyperphosphorylation.
The benzyl styryl sulfone, ON 01910.Na, is a novel anticancer agent that inhibits mitotic progression and induces apoptosis in… Expand
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2011
2011
Therapeutics , Targets , and Chemical Biology Effect of ON 01910 . Na , an Anticancer Mitotic Inhibitor , on Cell-Cycle Progression Correlates with RanGAP 1 Hyperphosphorylation
The benzyl styryl sulfone, ON 01910.Na, is a novel anticancer agent that inhibits mitotic progression and induces apoptosis in… Expand
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2009
2009
Importancia de la metilación y sumoilación de la coilina y del factor de supervivencia de las motoneuronas en el ensamblaje del cuerpo nuclear de Cajal
Los cuerpos nucleares de Cajal (CBs) son estructuras nucleares implicadas en la biogenesis de ribonucleoproteinas nucleares y… Expand
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