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SA 4503

Known as: SA-4503, SA4503 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Nootropic AgentsPiperazines

Narrower (1)

cutamesine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Evaluation of (+)-p-[11C]methylvesamicol for mapping sigma1 receptors: a comparison with [11C]SA4503.
2006
2006
Sigma1 and sigma2 receptor binding affinity and selectivity of SA4503 and fluoroethyl SA4503.
SA4503, a potent sigma(1) receptor agonist, is reported as having 103-fold higher affinity for sigma(1) (IC(50) = 17.4 nM) than… 
2004
2004
Tumor imaging with 2 sigma-receptor ligands, 18F-FE-SA5845 and 11C-SA4503: a feasibility study.
UNLABELLED Our objective was to study 2 radioligands for visualization of sigma-receptors with PET. METHODS Two radioligands… 
2003
2003
Different brain kinetics of two sigma1 receptor ligands, [3H](+)‐pentazocine and [11C]SA4503, by P‐glycoprotein modulation
We compared the brain kinetics of radiolabeled (+)‐pentazocine and SA4503, which have a high and selective affinity for sigma1… 
2003
2003
Evaluation of [18F]fluorinated sigma receptor ligands in the conscious monkey brain
PET‐imaging of the sigma receptors is very helpful to understand processes, e.g., several central nervous system (CNS)‐diseases… 
2002
2002
Synthesis and evaluation of [18F]fluoroethyl SA4503 as a PET ligand for the sigma receptor
The sigma receptor might be involved in several diseases in the central nervous system. It occurs in the endocrine, immune, and… 
2000
2000
In vivo evaluation of [(11)C]SA4503 as a PET ligand for mapping CNS sigma(1) receptors.
The potential of the (11)C-labeled selective sigma(1) receptor ligand 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine… 
Highly Cited
2000
Highly Cited
2000
Preclinical evaluation of [11C]SA4503: radiation dosimetry,in vivo selectivity and PET imaging of sigma1 receptors in the cat brain
Our previousin vivo study with rats has demonstrated that11C-labeled 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine… 
1997
1997
Synthesis, structure and quantitative structure-activity relationships of sigma receptor ligands, 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl) piperazines.
1997
1997
σ1 Receptor Subtype Is Involved in the Facilitation of Cortical Dopaminergic Transmission in the Rat Brain
Our previous studies have shown that three sigma (σ) receptor ligands, (+)-N-allylnormetazocine ((+)-SKF-10,047), (±)-pentazocine… 
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