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S Phase Cell Cycle Checkpoints

Known as: Checkpoints, S Phase, S-phase checkpoint, S Phase Cell Cycle Checkpoint 
Cell regulatory signaling system that controls progression through S PHASE and stabilizes the replication forks during conditions that could affect… 
National Institutes of Health

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Related topics

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aspects of radiation effectsphysiological aspects

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mitotic DNA replication checkpoint

Papers overview

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2016
2016
A role for the spindle assembly checkpoint in the DNA damage response
Spontaneous DNA damage poses a continuous threat to genomic integrity. If unchecked, genotoxic insults result in genomic… 
2011
2011
ATP-Dependent Chromatin Remodeling Factors Tune S Phase Checkpoint Activity
ABSTRACT The S phase checkpoint response slows down replication in the presence of replication stress such that replication can… 
2010
2010
Cyclin Regulation by the S Phase Checkpoint*
In eukaryotic cells a surveillance mechanism, the S phase checkpoint, detects and responds to DNA damage and replication stress… 
Highly Cited
2008
Highly Cited
2008
Regulation of Intra-S Phase Checkpoint by Ionizing Radiation (IR)-dependent and IR-independent Phosphorylation of SMC3*♦
Structure maintenance of chromosome 1 (SMC1) is phosphorylated by ataxia telangiectasia-mutated (ATM) in response to ionizing… 
Highly Cited
2007
Highly Cited
2007
Hst3 Is Regulated by Mec1-dependent Proteolysis and Controls the S Phase Checkpoint and Sister Chromatid Cohesion by Deacetylating Histone H3 at Lysine 56*
The SIR2 homologues HST3 and HST4 have been implicated in maintenance of genome integrity in the yeast Saccharomyces cerevisiae… 
2007
2007
A Novel Cell Cycle Inhibitor Stalls Replication Forks and Activates S Phase Checkpoint
DNA replication checkpoint is activated in response to replication stresses. It maintains the integrity of stalled replication… 
2005
2005
The yeast S phase checkpoint enables replicating chromosomes to bi-orient and restrain spindle extension during S phase distress
The budding yeast S phase checkpoint responds to hydroxyurea-induced nucleotide depletion by preventing replication fork collapse… 
Review
2004
Review
2004
Fanconi Anemia Proteins and the S Phase Checkpoint
DNA interstrand crosslinks (ICLs) repair represents a formidable task for mammalian cells. Indeed, such DNA lesions, bridging… 
Review
2003
Review
2003
Multiple Roles of Replication Forks in S Phase Checkpoints: Sensors, Effectors and Targets
There is mounting evidence that replication defects are the major source of spontaneous genomic instability in the cell and that… 
Highly Cited
1996
Highly Cited
1996
UVB radiation induces p21Cip1/WAF1 and mediates G1 and S phase checkpoints.
In a search for effectors and targets of UVB signaling in mammalian cells, we screened a keratinocyte cDNA library with… 
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