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S 5682

Known as: S-5682, S5682 
National Institutes of Health

Related topics

Related topics

5 relations
DaflonDetralex

Broader (3)

DiosminDrug CombinationsHesperidin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Effects of oral administration of different doses of purified micronized flavonoid fraction on microvascular reactivity after ischaemia/reperfusion in the hamster cheek pouch
1 The effects of a purified micronized flavonoid fraction (S5682) on mean internal diameter and blood flow of arterioles and… 
1997
1997
Oxidant-induced increase in vascular permeability is inhibited by oral administration of S-5682 (Daflon 500 mg) and alpha-tocopherol.
The aim was to study the effect of oral administration of three different doses of S-5682 and alpha-tocopherol on an oxidant… 
1997
1997
Microvascular Reactivity After Ischemia/Reperfusion in the Hamster Cheek Pouch: Beneficial Effects of Different Oral Doses of S-5682 (Daflon 500 mg)
Daflon 500 mg (S-5682) is a purified, micronized flavonoid fraction containing 90% diosmin and 10% hesperidin that is currently… 
1995
1995
Effects of oral administration of purified micronized flavonoid fraction on increased microvascular permeability induced by various agents and on ischemia/reperfusion in diabetic hamsters.
The effects of a clinically used purified micronized flavonoid fraction (S5682) containing 90% diosmin and 10% hesperidin on… 
Highly Cited
1993
Highly Cited
1993
A double-blind, placebo-controlled trial of a new veno-active flavonoid fraction (S 5682) in the treatment of symptomatic capillary fragility.
The efficacy and safety of a new veno-active flavonoid fraction (S 5682) consisting of micronized diosmin (90%) and hesperidin… 
1993
1993
Antioxidant activity of micronized diosmin on oxygen species from stimulated human neutrophils.
Highly Cited
1989
Highly Cited
1989
Protective effect of a purified flavonoid fraction against reactive oxygen radicals. In vivo and in vitro study.
S 5682 is a purified flavonoid fraction containing 90% diosmin (flavone derivative) and 10% hesperidin (flavanone derivative). In… 
1988
1988
Action of S 5682 on the complement system. In vitro and in vivo study.
Activation of the complement system during the early phase of inflammation is partly responsible for increased vascular… 
1988
1988
Effect of a flavonoid preparation (S 5682) on experimental capillary permeability increase in rat paw and rabbit skin.
S 5682 is constituted by a flavonoid mixture of 90% diosmin and 10% hesperidin. Its action has been studied in vivo on… 
Highly Cited
1987
Highly Cited
1987
Effect of chronic treatment with a purified flavonoid fraction on inflammatory granuloma in the rat. Study of prostaglandin E2 and F2 alpha and thromboxane B2 release and histological changes.
S-5682 (Daflon-500 mg), a purified flavonoid fraction, consisting of 90% diosmin (a flavone derivative) and 10% hesperidin (a… 
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