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Richter's syndrome

Known as: Richter's transformation, Richter transformation, Richter Syndrome 
Transformation of chronic lymphocytic leukemia into aggressive non-Hodgkin's lymphoma, usually diffuse large B-cell lymphoma (immunoblastic or… Expand
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Authors/Task Force Members (François Macha,∗,2, Colin Baigentb,∗∗,2, Alberico L. Catapanoc,∗∗∗,1,2, Konstantinos C. Koskinad… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Irreversible inhibition of Bruton's tyrosine kinase (BTK) by ibrutinib represents an important therapeutic advance for… Expand
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Highly Cited
2016
Highly Cited
2016
Despite promising results with targeted drugs, chemoimmunotherapy with fludarabine, cyclophosphamide (FC), and rituximab (R… Expand
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Highly Cited
2015
Highly Cited
2015
IMPORTANCE The Bruton tyrosine kinase (BTK) inhibitor ibrutinib is effective in patients with chronic lymphocytic leukemia (CLL… Expand
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Highly Cited
2012
Highly Cited
2012
Analysis of the chronic lymphocytic leukemia (CLL) coding genome has recently disclosed that the NOTCH1 proto-oncogene is… Expand
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Highly Cited
2011
Highly Cited
2011
Next generation sequencing and copy number analysis provide insights into the complexity of the CLL coding genome, and reveal an… Expand
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Review
2005
Review
2005
Richter's transformation denotes the development of high-grade non-Hodgkin lymphoma, prolymphocytic leukemia, Hodgkin disease, or… Expand
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Highly Cited
1998
Highly Cited
1998
PURPOSE To investigate the use of a nonmyeloablative fludarabine-based preparative regimen to produce sufficient… Expand
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Highly Cited
1998
Highly Cited
1998
One hundred seventy-four patients with progressive or advanced chronic lymphocytic leukemia (CLL) have received initial therapy… Expand
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Highly Cited
1991
Highly Cited
1991
We have investigated the frequency of p53 mutations in B- and T-cell human lymphoid malignancies, including acute lymphoblastic… Expand
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