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Ribonuclease H

Known as: Ribonuclease H [Chemical/Ingredient], RNase H, Endoribonuclease H 
A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Endoribonucleases
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Narrower (2)

ribonuclease H1ribonuclease HII

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Inhibition of HIV-1 Ribonuclease H by a Novel Diketo Acid, 4-[5-(Benzoylamino)thien-2-yl]-2,4-dioxobutanoic Acid*
Human immunodeficiency virus-type 1 (HIV-1) reverse transcriptase (RT) coordinates DNA polymerization and ribonuclease H (RNase H… 
Review
2002
Review
2002
Chimeric RNA-DNA molecular beacon assay for ribonuclease H activity.
Current methods to detect and assay ribonuclease H (RNase H) activity are indirect and time-consuming. Here we introduce a direct… 
1997
1997
Substituting a Conserved Residue of the Ribonuclease H Domain Alters Substrate Hydrolysis by Retroviral Reverse Transcriptase*
Alterations to the highly conserved Asp549 of the retroviral ribonuclease H (RNase H) domain were evaluated in the heterodimeric… 
Highly Cited
1994
Highly Cited
1994
Modulation of HIV-1 reverse transcriptase function in "selectively deleted" p66/p51 heterodimers.
Highly Cited
1993
Highly Cited
1993
Crystal structure of ribonuclease H from Thermus thermophilus HB8 refined at 2.8 A resolution.
The crystal structure of Thermus thermophilus RNase H was determined at 2.8 A resolution. The structure was solved by the… 
Highly Cited
1993
Highly Cited
1993
The interaction of illimaquinone, a selective inhibitor of the RNase H activity, with the reverse transcriptases of human immunodeficiency and murine leukemia retroviruses.
Highly Cited
1991
Highly Cited
1991
Human immunodeficiency virus reverse transcriptase displays a partially processive 3' to 5' endonuclease activity.
1990
1990
Purification and characterization of the RNase H domain of HIV‐1 reverse transcriptase expressed in recombinant Escherichia coli
Highly Cited
1973
Highly Cited
1973
Interchain disulfide bridges in ribonuclease BS-1.
Highly Cited
1963
Highly Cited
1963
Chromatographic separation of ribonucleases in corn.
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