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Rho GTPase-Activating Protein 5

Known as: p100 RasGAP-Associated p105 Protein, p190-B, Rho-Type GTPase-Activating Protein 5 
Rho GTPase-activating protein 5 (1502 aa, ~172 kDa) is encoded by the human ARHGAP5 gene. This protein is involved in GTPase activity regulation.
National Institutes of Health

Related topics

Related topics

7 relations
ARHGAP5 geneARHGAP5 wt AlleleCytoplasmFocal adhesion pathway

Papers overview

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2017
2017
p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation
The mechanisms regulating hematopoietic stem and progenitor cell (HSPC) fate choices remain ill-defined. Here, we show that a… 
2013
2013
Stressing HbF synthesis: role of translation?
In this issue of Blood , Hahn and Lowrey have identified phosphorylation of eukaryotic translation initiation factor 2α (eIF2… 
2013
2013
Hematopoietic Stem and Progenitor Cell Fate Decisions Are Regulated By a Cell-Autonomous p190-B/TGF-β Signaling Pathway
Hematopoietic stem cells (HSC) are undifferentiated cells that self-renew and produce all mature blood and immune cells in order… 
2011
2011
P190-B RhoGAP Is Critical for Hematopoietic Stem Cell Niche Regulation
Abstract 221 Hematopoiesis is regulated by components of the stromal microenvironment, so-called niche. Although the concept of… 
2006
2006
P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland.
p190-B Rho GTPase activating protein is essential for mammary gland development because p190-B deficiency prevents ductal… 
Highly Cited
2004
Highly Cited
2004
SHP-2 Positively Regulates Myogenesis by Coupling to the Rho GTPase Signaling Pathway
ABSTRACT Myogenesis is an intricate process that coordinately engages multiple intracellular signaling cascades. The Rho family… 
Highly Cited
2003
Highly Cited
2003
p190-B RhoGAP regulates mammary ductal morphogenesis.
Previous studies from our laboratory have demonstrated that p190-B RhoGAP (p190-B) is differentially expressed in the Cap cells… 
2003
2003
Response: Binocular rivalry and perceptual multi-stability
Highly Cited
2000
Highly Cited
2000
p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas.
2000
2000
P190-B, a Rho-GTPase-activating protein, is differentially expressed in terminal end buds and breast cancer.
Microdissection and differential display PCR were used to identify genes preferentially expressed in the highly proliferative… 
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