Retinoid X Receptor gamma
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The liver is the most important tissue site in the body for uptake of postprandial retinoid, as well as for retinoid storage… Expand The Vitamin A metabolite, retinoic acid, has been shown to have chemopreventive and therapeutic activity for certain cancers such… Expand The growth of any solid tumor depends on angiogenesis. Vascular endothelial growth factor (VEGF) plays a prominent role in… Expand In a search for retinoic acid (RA) receptor ligands endowed with potent apoptotic activity, a series of novel arotinoids were… Expand Vitamin A and retinoids affect pituitary-thyroid function through suppression of serum thyroid-stimulating hormone (TSH) levels… Expand The novel synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) has been shown to induce… Expand Approximately 25% of postprandial retinoid is cleared from the circulation by extrahepatic tissues. Little is known about… Expand Human malignant melanoma is notoriously resistant to pharmacological modulation. We describe here for the first time that the… Expand Retinoic acid receptors (RARs) modulate gene expression following association with retinoic acid (RA). In transient transfection… Expand