Replication Error

Known as: RER 
A Replication Error results from the covalent addition of an incorrect nucleotide subunit, or the lack of addition of a nucleotide subunit, during… (More)
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
DNA replication−associated mutations are repaired by two components: polymerase proofreading and mismatch repair. The mutation… (More)
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2014
2014
Genetic defects in DNA polymerase accuracy, proofreading, or mismatch repair (MMR) induce mutator phenotypes that accelerate… (More)
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Highly Cited
2009
Highly Cited
2009
Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a rare, neonatally lethal developmental disorder… (More)
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2000
2000
The inversion-angle replication error of the ankle joint was measured in subjects with a functionally stable or unstable ankle… (More)
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Highly Cited
1997
Highly Cited
1997
Instability of microsatellites is a hallmark of the DNA replication error phenotype (RER+) due to the inactivation of mismatch… (More)
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Highly Cited
1997
Highly Cited
1997
Beta-catenin has been identified as an oncogene in colon cancer and melanoma. Phosphorylation of sites in exon 3 of beta-catenin… (More)
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Highly Cited
1996
Highly Cited
1996
Loss of heterozygosity (LOH) and replication error (RER) are important phenomena in tumor development, with diagnostic and… (More)
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Highly Cited
1995
Highly Cited
1995
Escape from negative growth regulation by transforming growth factor beta (TGF-beta) as a result of the loss of TGF-beta type II… (More)
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Highly Cited
1993
Highly Cited
1993
Mutation of predicted 3'-->5' exonuclease active site residues of Saccharomyces cerevisiae POL3 DNA polymerase (delta) or… (More)
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Highly Cited
1992
Highly Cited
1992
The use of unequal concentrations of the four deoxynucleoside triphosphates (dNTPs) in DNA polymerization reactions alters base… (More)
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