Replication Competent Retrovirus

Known as: RCR, Replication-Competent Retroviruses, Replication-Competent Retrovirus 
A retroviral vector that contains all the genes that are required for virion synthesis and is able to propagate after the host is infected.
National Institutes of Health

Papers overview

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2009
2009
Detection of replication competent retrovirus and lentivirus.
Retroviral vectors based on murine leukemia viruses (MuLV) have been used in clinical investigations for over a decade… (More)
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Review
2008
Review
2008
Replication-competent retrovirus vectors for cancer gene therapy.
Oncolytic virotherapy represents an emerging field with tremendous promise for harnessing the replicative capabilities of viruses… (More)
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Highly Cited
2006
Highly Cited
2006
Cuff integrity after arthroscopic versus open rotator cuff repair: a prospective study.
Arthroscopic rotator cuff repair (RCR) has been reported to have good clinical results but high retear rates by ultrasound. We… (More)
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2005
2005
Single-shot, multicycle suicide gene therapy by replication-competent retrovirus vectors achieves long-term survival benefit in experimental glioma.
Achieving therapeutically efficacious levels of gene transfer in tumors has been a major obstacle for cancer gene therapy using… (More)
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Highly Cited
2000
Highly Cited
2000
Plat-E: an efficient and stable system for transient packaging of retroviruses
A potent retrovirus packaging cell line named Platinum-E (Plat-E) was generated based on the 293T cell line. Plat-E is superior… (More)
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Highly Cited
1998
Highly Cited
1998
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery.
In vivo transduction of nondividing cells by human immunodeficiency virus type 1 (HIV-1)-based vectors results in transgene… (More)
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Review
1998
Review
1998
Targeted gene misexpression in chick limb buds using avian replication-competent retroviruses.
The methods and applications for using avian replication-competent retroviruses to target gene misexpression in the developing… (More)
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Highly Cited
1998
Highly Cited
1998
Signal amplification of padlock probes by rolling circle replication.
Circularizing oligonucleotide probes (padlock probes) have the potential to detect sets of gene sequences with high specificity… (More)
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Highly Cited
1992
Highly Cited
1992
Conserved sequence motifs in the initiator proteins for rolling circle DNA replication encoded by diverse replicons from eubacteria, eucaryotes and archaebacteria
An amino acid motif was identified that consists of the sequence HisHydrHisHydrHydrHydr (Hydr--bulky hydrophobic residue) and is… (More)
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Highly Cited
1991
Highly Cited
1991
Replication-competent retrovirus vectors for the transfer and expression of gene cassettes in avian cells.
We have constructed a series of replication-competent retrovirus vectors to introduce and express gene cassettes in avian cells… (More)
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