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Top 100 relevant results, sorted by most influential
Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation
Human T-cell leukaemia viruses (HTLVs) have genomic organization distinct from that of other replication-competent retroviruses, possessing four genes, gag, pol, env and χ. The unique fourth gene, χ… Expand
Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma.
Rituximab plus intravenous bolus chemotherapy is a standard treatment for immunocompetent patients with B-cell non-Hodgkin lymphoma (NHL). Some studies have suggested that rituximab is associated… Expand
Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow.
- W. Hofmann, S. de Vos, M. Komor, D. Hoelzer, W. Wachsman, H. Koeffler
- Biology, Medicine
- 15 November 2002
Gene patterns of expression in purified CD34(+) bone marrow cells from 7 patients with low-risk myelodysplastic syndrome (MDS) and 4 patients with high-risk MDS were compared with expression data… Expand
Early viral brain invasion in iatrogenic human immunodeficiency virus infection
We report a 68-year-old man who received an IV inoculation of WBCs for an indium radionuclide scan containing 600 to 700 tissue culture infectious doses of human immunodeficiency virus type 1 (HIV-1)… Expand
In silico dissection of cell-type-associated patterns of gene expression in prostate cancer.
- R. O. Stuart, W. Wachsman, +12 authors D. Mercola
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 13 January 2004
Prostate tumors are complex entities composed of malignant cells mixed and interacting with nonmalignant cells. However, molecular analyses by standard gene expression profiling are limited because… Expand
Repression of IL-2 Promoter Activity by the Novel Basic Leucine Zipper p21SNFT Protein1 2
IL-2 is the major autocrine and paracrine growth factor produced by T cells upon T cell stimulation. The inducible expression of IL-2 is highly regulated by multiple transcription factors,… Expand
Cell Cycle Alterations in the Blastoid Variant of Mantle Cell Lymphoma (MCL-BV) as Detected by Gene Expression Profiling of Mantle Cell Lymphoma (MCL) and MCL-BV
- S. de Vos, U. Krug, +6 authors H. Koeffler
- Medicine, Biology
- Diagnostic molecular pathology : the American…
- 1 March 2003
Overexpression of cyclin D1 is necessary but by itself insufficient for the development of mantle cell lymphoma (MCL). To identify pathways in the pathogenesis of MCL and the blastoid variant… Expand
Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray.
An imbalance between cellular apoptosis and survival may be critical for the pathogenesis of lymphoma. Therefore, the gene expression pattern in lymph node preparations from patients with mantle cell… Expand
Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis
Together with glial-derived neurotrophic factor (GDNF), soluble factors present in a metanephric mesenchyme (MM) cell conditioned medium (BSN-CM) are necessary to induce branching morphogenesis of… Expand
Noninvasive genomic detection of melanoma
Background Early detection and treatment of melanoma is important for optimal clinical outcome, leading to biopsy of pigmented lesions deemed suspicious for the disease. The vast majority of such… Expand