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Recombinant Tyrosinase-Related Protein-2

Known as: TRP-2, Tyrosinase-Related Protein-2 
A recombinant therapeutic agent which is chemically identical to or similar to an endogenous non-mutated melanocyte differentiation antigen expressed… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2015
01219972015

Related topics

Related topics

2 relations
Dopachrome isomerasedopachrome isomerase activity

Related mentions per year

Related mentions per year

1967-2018
1960198020002020
Recombinant Tyrosinase-Related Protein-2
Dopachrome isomerase
dopachrome isomerase activity

Papers overview

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2014
2014
Melanogenesis Inhibitory Activity in the Extracts of Oreocnide fruticosa (Gaudich.) Hand.-Mazz. Branches
Article history: Received on: 17/11/2013 Revised on: 19/12/2013 Accepted on: 26/01/2014 Available online: 30/01/2014 Development… (More)
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2010
2010
Depigmenting mechanism of NSAIDs on B16F1 melanoma cells
The aim of the present work was to clarify the anti-melanogenic mechanism of non-steroidal anti-inflammatory drugs (NSAIDs… (More)
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2009
2009
MART-1 transcript is absent in PBMCs from Vitiligo patients
Mechanisms occurring in the thymus and periphery are responsible for the generation and maintenance of tolerance in the immune… (More)
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2008
2008
TRP-2 specifically decreases WM35 cell sensitivity to oxidative stress.
TRP-2 (dopachrome tautomerase) is a melanogenic enzyme whose expression was recently reported to modulate melanocyte response to… (More)
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2008
2008
TRP-2 expression protects HEK cells from dopamine- and hydroquinone-induced toxicity.
We previously reported that melanogenic enzyme TRP-2 (or DCT for DOPAchrome tautomerase) expression in WM35 melanoma cells… (More)
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2006
2006
Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Rα2, gp100 and TRP-2 for immunotherapy
In this study, we investigated the mRNA and protein expression of nine tumour antigens in human glioblastoma multiforme with a… (More)
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2004
2004
Absence of TRP-2 in melanogenic melanocytes of human hair.
Skin and hair colour mostly depend on the activity of melanogenic melanocytes. Numerous proteins involved in melanocyte function… (More)
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2002
2002
Pre-existing immunity to tyrosinase-related protein (TRP)-2, a new TRP-2 isoform, and the NY-ESO-1 melanoma antigen in a patient with a dramatic response to immunotherapy.
We have performed a detailed analysis of the recognition of melanoma Ags by the tumor-infiltrating lymphocytes (TIL) 1790… (More)
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2001
2001
Therapeutic tumor immunity induced by polyimmunization with melanoma antigens gp100 and TRP-2.
To improve the immunogenicity of melanoma self-antigens, we used a novel strategy of nonviral genetic vaccination coupled with… (More)
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Highly Cited
1997
Highly Cited
1997
Identification of Tyrosinase-related Protein 2 as a Tumor Rejection Antigen for the B16 Melanoma
Recently, major advances have been made in the identification of antigens from human melanoma which are recognized by T cells. In… (More)
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