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Recombinant Tyrosinase-Related Protein-2

Known as: TRP-2, Tyrosinase-Related Protein-2 
A recombinant therapeutic agent which is chemically identical to or similar to an endogenous non-mutated melanocyte differentiation antigen expressed… Expand
National Institutes of Health

Related topics

Related topics

2 relations
Dopachrome isomerasedopachrome isomerase activity

Papers overview

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2020
2020
Exploring the potential effect and mechanisms of protocatechuic acid on human hair follicle melanocytes
Abstract This study aims to evaluate the effect of protocatechuic acid (PCA) on human hair follicle melanocytes (HFM). Normal… Expand
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2019
2019
Molecular Basis for Membrane Selectivity of Antimicrobial Peptide Pleurocidin in the Presence of Different Eukaryotic and Prokaryotic Model Membranes.
Pleurocidin, a 25-residue cationic peptide, has antimicrobial activity against bacteria and fungi but exhibits very low hemolytic… Expand
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2010
2010
Effect of δ-tocotrienol on melanin content and enzymes for melanin synthesis in mouse melanoma cells.
In the present study, we investigated the dose-dependent effect of delta-tocotrienol long term (48, 72 h) on the melanin content… Expand
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2008
2008
TRP-2 specifically decreases WM35 cell sensitivity to oxidative stress.
TRP-2 (dopachrome tautomerase) is a melanogenic enzyme whose expression was recently reported to modulate melanocyte response to… Expand
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2003
2003
Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant glioma.
Tyrosinase-related protein (TRP)-2 is an immunogenic antigen in melanoma. The authors sought to investigate whether TRP-2 could… Expand
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2001
2001
Alternative roles for interferon-gamma in the immune response to DNA vaccines encoding related melanosomal antigens.
Tyrosinase-related proteins-1 and -2 (gp75/TRP-1 and TRP-2) are melanosomal membrane glycoproteins recognized by antibodies and T… Expand
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Highly Cited
1999
Highly Cited
1999
Coupling and Uncoupling of Tumor Immunity and Autoimmunity
Self-antigens, in the form of differentiation antigens, are commonly recognized by the immune system on melanoma and other… Expand
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1996
1996
Regulation of melanogenesis in B16 mouse melanoma cells by protein kinase C.
Melanogenesis is regulated by a variety of environmental and hormonal factors. In this study, we showed that protein kinase C… Expand
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