dopachrome isomerase activity

Known as: TRP2, dopachrome delta7,Delta2-isomerase activity, dopachrome-rearranging enzyme 
Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate. [EC:5.3.3.12, RHEA:13044]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2018
024619672018

Papers overview

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2012
2012
AIM Plant cannabinoids, like Δ(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD), activate/desensitize thermosensitive… (More)
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2009
2009
Many antigens recognized by tumor-reactive cytotoxic CD8+ T cells are self-antigens. Tyrosinase-related protein 2 (TRP-2) is a… (More)
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2009
2009
BACKGROUND Increased production and accumulation of melanin leads to various hyperpigmentation disorders. Melanin synthesis is… (More)
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2003
2003
Tyrosinase-related protein (TRP)-2 is an immunogenic antigen in melanoma. The authors sought to investigate whether TRP-2 could… (More)
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2000
2000
In this paper, we present a JPEC-compliant method for the efficient compression of compound documents using variable quantization… (More)
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1998
1998
Macrophage-migration-inhibition factor (MIF) is an essential stimulator of mammalian T-lymphocyte-dependent adaptive immunity… (More)
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1994
1994
Melanin synthesis of follicular melanocytes is strictly coupled to the growth stage of the hair cycle (anagen), ceases during… (More)
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1993
1993
Melanin is specifically produced in melanocytes. The pathway for melanin biosynthesis is regulated by a number of melanocyte… (More)
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Highly Cited
1992
Highly Cited
1992
We have used a probe derived from TRP-2/DT to detect migratory melanoblasts shortly after they emerge from the neural crest, as… (More)
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Highly Cited
1992
Highly Cited
1992
The production of melanin pigment in mammals requires tyrosinase, an enzyme which hydroxylates the amino acid tyrosine to DOPA (3… (More)
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