Recombinant Interleukin-17

Known as: CTLA-8 (Therapeutic), IL-17, Interleukin-17 
A recombinant agent, which is chemically identical or similar to the endogenous cytokine interleukin-17 (IL-17). IL-17 is produced by cytotoxic T… (More)
National Institutes of Health

Related topics

Related topics

7 relations
IL-17 activityIL-17E binding activityIL17A geneIL25 gene
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Papers overview

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Review
2017
Review
2017
IL-17 and IL-22 in immunity: Driving protection and pathology.
IL-17 and IL-22 are tissue-signaling cytokines that favor protection and regeneration of barrier organs such as the skin, lung… (More)
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Review
2017
Review
2017
The Role of IL-17 and Related Cytokines in Inflammatory Autoimmune Diseases
Interleukin-17 (IL-17) induces the production of granulocyte colony-stimulating factor (G-CSF) and chemokines such as CXCL1 and… (More)
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Highly Cited
2012
Highly Cited
2012
Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis.
BACKGROUND Type 17 helper T cells have been suggested to play a pathological role in psoriasis. They secrete several… (More)
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Highly Cited
2009
Highly Cited
2009
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals.
Gammadelta T cells are an innate source of interleukin-17 (IL-17), preceding the development of the adaptive T helper 17 (Th17… (More)
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Highly Cited
2009
Highly Cited
2009
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
The intestinal flora may promote colon tumor formation. Here we explore immunologic mechanisms of colonic carcinogenesis by a… (More)
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Highly Cited
2009
Highly Cited
2009
The interleukin-17 pathway is involved in human alcoholic liver disease.
UNLABELLED Immune dysregulations in alcoholic liver diseases are still unclear, especially regarding alcoholic hepatitis… (More)
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Highly Cited
2008
Highly Cited
2008
A microbial symbiosis factor prevents intestinal inflammatory disease
Humans are colonized by multitudes of commensal organisms representing members of five of the six kingdoms of life; however, our… (More)
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Highly Cited
2003
Highly Cited
2003
Interleukin-17 promotes angiogenesis and tumor growth.
Interleukin-17 (IL-17) is a CD4 T-cell-derived proinflammatory cytokine. We investigated the effects of locally produced IL-17 by… (More)
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Highly Cited
2002
Highly Cited
2002
Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses.
Interleukin-17 (IL-17) is a proinflammatory cytokine produced by T cells. The involvement of IL-17 in human diseases has been… (More)
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Highly Cited
2000
Highly Cited
2000
Increased interleukin-17 production in patients with systemic sclerosis.
OBJECTIVE To determine the role of a novel T cell-derived cytokine, interleukin-17 (IL-17), which activates fibroblasts and… (More)
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