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Recombinant Human Adenovirus Type 5 H101

Known as: H101, rAd5 H101 
A replication selective, recombinant, E1B and partial E3 gene deleted form of human adenovirus type 5, with potential antineoplastic activity. Upon… 
National Institutes of Health

Papers overview

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2016
2016
Effects of Gabra2 Point Mutations on Alcohol Intake: Increased Binge-Like and Blunted Chronic Drinking by Mice.
BACKGROUND Alcohol use disorders are associated with single-nucleotide polymorphisms in GABRA2, the gene encoding the GABAA… 
2012
2012
Therapeutic Efficacy by Targeting Correction of Notch1-Induced Aberrants in Uveal Tumors
There is a need for more effective treatments for uveal melanoma. The recombinant oncolytic adenovirus H101 replicates… 
Review
2007
Review
2007
Oncolytic virus therapy--foreword.
We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus… 
2006
2006
Gene therapy finds welcoming environment in China
China in November became the first country to have approved two drugs based on gene therapy. The approvals have fueled quick… 
2005
2005
Structural Analysis of Divalent Metals Binding to the Bacillus subtilis Response Regulator Spo0F: The Possibility for In Vitro Metalloregulation in the Initiation of Sporulation
The presence of a divalent metal ion in a negatively charged aspartic acid pocket is essential for phosphorylation of response… 
2004
2004
Theoretical investigation of the origins of catalysis of a retro-Diels-Alder reaction by antibody 10F11.
The antibody 10F11 catalyzes a retro-Diels-Alder reaction that forms HNO. Deductions about the mechanism of catalysis were made… 
Highly Cited
2000
Highly Cited
2000
Alterations in cytokine but not chemokine mRNA expression during three distinct Theiler’s virus infections
Highly Cited
1998
Highly Cited
1998
Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Arginase is a thermostable (Tm = 75 degrees C) binuclear manganese metalloenzyme which hydrolyzes l-arginine to form l-ornithine… 
1997
1997
Hydrocephalus in Mice Infected with a Theiler's Murine Encephalomyelitis Virus Variant
The etiology of hydrocephalus is never established in the majority of clinical cases, while various agents, nutritional… 
1990
1990
Computer analysis of mutations that affect antibody specificity
The mouse hybridoma cell line 40–150 scretes antibodies with high affinity towards the cardiac glycosides digoxin and digitoxin… 
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