Receptor, Serotonin, 5-HT2A

Known as: Receptor, 5-HT2A, 5-HT(2A) Receptor, 5-HT2A Receptor 
A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that… (More)
National Institutes of Health

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Papers overview

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Highly Cited
2006
Highly Cited
2006
Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice.
Serotonin [5-hydroxytryptamine (5-HT)] neurotransmission in the central nervous system modulates depression and anxiety-related… (More)
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Highly Cited
2004
Highly Cited
2004
Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia.
BACKGROUND Alterations of serotonin neurotransmission are implicated in both mood disorders and schizophrenia. Specific serotonin… (More)
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Highly Cited
2003
Highly Cited
2003
The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism
In the present series of studies, we have investigated the effects of antagonists selective for the 5-HT2A, 5-HT2B and 5-HT2C… (More)
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Highly Cited
2002
Highly Cited
2002
Differential Effects of the 5-HT2A Receptor Antagonist M100,907 and the 5-HT2C Receptor Antagonist SB242,084 on Cocaine-induced Locomotor Activity, Cocaine Self-administration and Cocaine-induced…
These studies investigated the effects of antagonists selective for the 5-HT2A, 5-HT2B, or 5-HT2C receptor subtypes on behaviors… (More)
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Highly Cited
2000
Highly Cited
2000
Segregation of serotonin 5-HT2A and 5-HT3 receptors in inhibitory circuits of the primate cerebral cortex.
An emerging concept of cortical network organization is that distinct segments of the pyramidal neuron tree are controlled by… (More)
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Highly Cited
1999
Highly Cited
1999
Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients.
OBJECTIVE Multicenter trials with the novel antipsychotic risperidone have suggested a standard dose of 6 mg/day. However, a dose… (More)
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Highly Cited
1999
Highly Cited
1999
M100907, a Serotonin 5-HT2A Receptor Antagonist and Putative Antipsychotic, Blocks Dizocilpine-Induced Prepulse Inhibition Deficits in Sprague–Dawley and Wistar Rats
In a recent study using Wistar rats, the serotonergic 5-HT2 receptor antagonists ketanserin and risperidone reduced the… (More)
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Highly Cited
1997
Highly Cited
1997
5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex.
The influence of 5-HT receptor agonists on the expression of BDNF in brain was determined. Administration of a hallucinogenic 5… (More)
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Highly Cited
1997
Highly Cited
1997
Direct injection of 5-HT2A receptor agonists into the medial prefrontal cortex produces a head-twitch response in rats.
The serotonin (5-HT)(2A/2c) agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), the 5-HT2C agonist 6-chloro-2-[1… (More)
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Highly Cited
1996
Highly Cited
1996
5-HT1A and 5-HT2A Receptor mRNAs and Binding Site Densities Are Differentially Altered in Schizophrenia
We have investigated 5-HT1A (serotonin1A) and 5-HT2A (serotonin2A) receptor mRNA abundance and binding site densities in various… (More)
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