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Receptor, Serotonin, 5-HT2A

Known as: Receptor, 5-HT2A, 5-HT(2A) Receptor, 5-HT2A Receptor 
A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that… Expand
National Institutes of Health

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5 relations
HTR2A geneHTR2A protein, humanIn Bloodaspects of radiation effects
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Papers overview

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Highly Cited
2006
Highly Cited
2006
Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice
Serotonin [5-hydroxytryptamine (5-HT)] neurotransmission in the central nervous system modulates depression and anxiety-related… Expand
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Highly Cited
2006
Highly Cited
2006
Molecular Interaction of Serotonin 5-HT2A Receptor Residues Phe339(6.51) and Phe340(6.52) with Superpotent N-Benzyl Phenethylamine Agonists
Experiments were conducted to examine the molecular basis for the high affinity and potency of a new class of 5-HT2A receptor… Expand
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Highly Cited
2006
Highly Cited
2006
Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: an in vivo SPECT study.
OBJECTIVE The cause of autistic spectrum disorder (i.e., autism and Asperger's syndrome) is unknown. The serotonergic (5-HT… Expand
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Highly Cited
2006
Highly Cited
2006
Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.
Depressive disorders account for a large and increasing global burden of disease. Although the condition of many patients… Expand
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Highly Cited
2004
Highly Cited
2004
Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia
BACKGROUND Alterations of serotonin neurotransmission are implicated in both mood disorders and schizophrenia. Specific serotonin… Expand
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Highly Cited
2000
Highly Cited
2000
Serotonin receptor subtypes involved in the spinal antinociceptive effect of 5-HT in rats
&NA; The present study was designed to investigate which subtypes of spinal 5‐HT receptors are involved in 5‐HT‐induced… Expand
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Highly Cited
1999
Highly Cited
1999
Cellular and subcellular distribution of the serotonin 5‐HT2A receptor in the central nervous system of adult rat
Light and electron microscope immunocytochemistry with a monoclonal antibody against the N‐terminal domain of the human protein… Expand
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Highly Cited
1997
Highly Cited
1997
Serotonin Induces Excitatory Postsynaptic Potentials in Apical Dendrites of Neocortical Pyramidal Cells
By intracellular and whole cell recording in rat brain slices, it was found that bath-applied serotonin (5-HT) produces an… Expand
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Highly Cited
1997
Highly Cited
1997
Direct injection of 5-HT2A receptor agonists into the medial prefrontal cortex produces a head-twitch response in rats.
The serotonin (5-HT)(2A/2c) agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), the 5-HT2C agonist 6-chloro-2-[1… Expand
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Highly Cited
1996
Highly Cited
1996
Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile.
In preclinical studies, [R-(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4- piperidinemethanol] [formula: see text… Expand
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